| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA904107 | T | CNS toxicity in iv dosed Sprague-Dawley rat assessed as cumulative convulsion dose | Rattus norvegicus | 52 | organism-based format | Scientific Literature | ||
| 2. | ALA904108 | F | Hemodynamic effect in intravenously dosed Sprague-Dawley rat with ischemia-induced arrhythmia assessed as dose producing 25% reduction in systemic blood pressure | Rattus norvegicus | 22 | organism-based format | Scientific Literature | ||
| 3. | ALA904109 | F | Antiarrhythmic activity in intravenously dosed Sprague-Dawley rat with ischemia-induced arrhythmia | Rattus norvegicus | 43 | organism-based format | Scientific Literature | ||
| 4. | ALA905103 | F | Effect on blood pressure in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% change in arterial blood pressure | Rattus norvegicus | 25 | organism-based format | Scientific Literature | ||
| 5. | ALA905104 | F | Effect on ECG parameters in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% prolongation of P-R interval | Rattus norvegicus | 23 | organism-based format | Scientific Literature | ||
| 6. | ALA905105 | F | Effect on ECG parameters in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% lengthening in QT1 interval | Rattus norvegicus | 25 | organism-based format | Scientific Literature | ||
| 7. | ALA905106 | F | Effect on ECG parameters in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% lengthening in QT2 interval | Rattus norvegicus | 26 | organism-based format | Scientific Literature | ||
| 8. | ALA905107 | F | Effect on electrical stimulation in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% prolongation of in current threshold for induction of extrasystole | Rattus norvegicus | 27 | organism-based format | Scientific Literature | ||
| 9. | ALA905108 | F | Effect on electrical stimulation in intravenously dosed Sprague-Dawley rat assessed as dose producing 25% increase in effective refractory period | Rattus norvegicus | 27 | organism-based format | Scientific Literature | ||
| 10. | ALA905109 | T | Toxicity in intravenously dosed CD1 mouse | Mus musculus | 27 | organism-based format | Scientific Literature | ||
| 11. | ALA905110 | B | Inhibition of human heart sodium channel Nav1.5 by patch-clamp method | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 12. | ALA905111 | B | Inhibition of human potassium channel Kv1.5 by patch-clamp method | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 13. | ALA905112 | B | Inhibition of rat potassium channel Kv4.2 by patch-clamp method | Rattus norvegicus | 7 | single protein format | Scientific Literature | ||
| 14. | ALA905113 | B | Inhibition of rat potassium channel Kv2.1 by patch-clamp method | Rattus norvegicus | 7 | single protein format | Scientific Literature | ||
| 15. | ALA905119 | A | Half life in Wistar rat at 17 mg/kg. iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA905121 | A | Volume of distribution at steady state in Wistar rat at 17 mg/kg. iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA905123 | A | Clearance in Wistar rat at 17 mg/kg. iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA905125 | A | Oral bioavailability in Wistar rat at 34 mg/kg. iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA905126 | F | Reduction of blood pressure in Mongrel dog vagal atrial fibrillation model | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 20. | ALA905127 | F | Reduction of heart rate in Mongrel dog vagal atrial fibrillation model | Canis lupus familiaris | 3 | organism-based format | Scientific Literature |
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