| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA905612 | A | Permeability coefficient through artificial membrane in presence of unstirred water layer by PAMPA | 97 | assay format | Scientific Literature | |||
| 2. | ALA905616 | A | Permeability from apical to basolateral side of the Caco-2 cell membrane | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA905617 | A | Permeability from basolateral to apical side of the Caco-2 cell membrane | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA905619 | A | Membrane retention in permeability experiment with artificial membrane | 37 | assay format | Scientific Literature | |||
| 5. | ALA905620 | P | Partition coefficient, log P of the compound | 96 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA2114890 | F | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | Homo sapiens | 1,142 | assay format | PubChem BioAssays | ||
| 7. | ALA926149 | F | Larvicidal activity against Oriental armyworm | Mythimna separata | 33 | organism-based format | Scientific Literature | ||
| 8. | ALA1794524 | F | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) | 384 | assay format | PubChem BioAssays | |||
| 9. | ALA2114797 | F | PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) | Rattus norvegicus | 424 | assay format | PubChem BioAssays | ||
| 10. | ALA1243411 | A | Toxicity in zebrafish AB embryos assessed as induction of patterning deffects at 10 uM single dose measured 72 hrs post fertilization | Danio rerio | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA1243412 | A | Toxicity in zebrafish AB embryos assessed as induction of patterning deffects at 10 uM dosed every 24 hrs measured 72 hrs post fertilization | Danio rerio | 4 | organism-based format | Scientific Literature | ||
| 12. | ALA1243413 | B | Activation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (468-490) at 50 uM exposed for 2 to 6 hrs at 4 hrs post fertilization by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature | ||
| 13. | ALA1243414 | B | Induction of nuclear translocation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (468-490) at 1 uM exposed for 30 mins at 4 hrs post fertilization by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature | ||
| 14. | ALA1243415 | B | Activation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606)-mediated myl7 gene expression expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (468-490) assessed as myl7-promoter driven heart specific GFP expression at 10 uM exposed during 3 to 48 hrs post fertilization by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature | ||
| 15. | ALA1243416 | B | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (413-490) at 10 uM exposed for 16 hrs by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature | ||
| 16. | ALA1243417 | B | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (413-456) at 10 uM exposed for 16 hrs by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature | ||
| 17. | ALA1243418 | B | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (413-468) at 10 uM exposed for 16 hrs by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature | ||
| 18. | ALA1243419 | B | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (413-476) at 10 uM exposed for 16 hrs by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature | ||
| 19. | ALA1243420 | B | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (456-490) at 10 uM exposed for 16 hrs by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature | ||
| 20. | ALA1243421 | B | Activation of Bombyx mori Ecdysone receptor (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (468-490) at 10 uM exposed for 16 hrs by Gal4 dependent luciferase reportre gene assay relative to untreated control | Bombyx mori | 1 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!