| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA889279 | B | Inhibition of SCD1 in ob/ob mouse liver microsome | Mus musculus | 55 | assay format | Scientific Literature | ||
| 2. | ALA889281 | B | Inhibition of human recombinant SCD1 expressed in S6 cells | Homo sapiens | 52 | cell-based format | Scientific Literature | ||
| 3. | ALA889282 | A | Metabolic stability in ob/ob mouse liver microsome | Mus musculus | 55 | assay format | Scientific Literature | ||
| 4. | ALA889283 | A | Metabolic stability in Sprague-Dawley rat liver microsome | Rattus norvegicus | 55 | microsome format | Scientific Literature | ||
| 5. | ALA2321446 | F | In vivo inhibition of SCD1 in Lewis rat liver microsome at 15 mg/kg, ip administered qd for 2 days | Rattus norvegicus | 12 | organism-based format | Scientific Literature | ||
| 6. | ALA2321448 | A | Metabolic stability in rat liver microsome after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 51 | microsome format | Scientific Literature | ||
| 7. | ALA2321449 | A | Protein binding in plasma (unknown origin) | Not specified | 1 | cell-free format | Scientific Literature | ||
| 8. | ALA2321450 | A | Apparent permeability from apical to basolateral side in human Caco2 cells | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 9. | ALA2321451 | A | Inhibition of CYP2D6 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA2321452 | A | Inhibition of CYP2C19 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA2321453 | A | Inhibition of CYP2C9 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA2321454 | A | Inhibition of CYP3A4 (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA2321455 | B | Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrs | Homo sapiens | 56 | cell-based format | Scientific Literature | ||
| 14. | ALA2321456 | B | Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water after 20 hrs by scintillation counting analysis | Mus musculus | 57 | microsome format | Scientific Literature |
The page will load shortly, Thanks for your patience!