# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA889606 | Binding | Inhibition of Pneumocystis carinii DHFR | Pneumocystis carinii | 22 | ALA1145401 | single protein format | Scientific Literature | |
2. | ALA889609 | Binding | Inhibition of Toxoplasma gondii DHFR | Toxoplasma gondii | 23 | ALA1145401 | single protein format | Scientific Literature | |
3. | ALA889610 | Binding | Inhibition of Mycobacterium avium DHFR | Mycobacterium avium | 23 | ALA1145401 | single protein format | Scientific Literature | |
4. | ALA907539 | Binding | Inhibition of rat liver DHFR | Rattus norvegicus | 23 | ALA1145401 | assay format | Scientific Literature | |
5. | ALA907540 | Binding | Selectivity ratio of IC50 for rat liver DHFR to IC50 for Pneumocystis carinii DHFR | 23 | ALA1145401 | assay format | Scientific Literature | ||
6. | ALA907541 | Binding | Selectivity ratio of IC50 for rat liver DHFR to IC50 for Toxoplasma gondii DHFR | 23 | ALA1145401 | assay format | Scientific Literature | ||
7. | ALA907542 | Binding | Selectivity ratio of IC50 for rat liver DHFR to IC50 for Mycobacterium avium DHFR | 23 | ALA1145401 | assay format | Scientific Literature | ||
8. | ALA1071426 | Binding | Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assay | Toxoplasma gondii | 5 | ALA1156926 | single protein format | Scientific Literature | |
9. | ALA1071427 | Binding | Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assay | Rattus norvegicus | 5 | ALA1156926 | assay format | Scientific Literature | |
10. | ALA1071429 | Binding | Selectivity for Toxoplasma gondii DHFR over rat liver DHFR | 5 | ALA1156926 | assay format | Scientific Literature | ||
11. | ALA4224045 | Binding | Inhibition of Pneumocystis jirovecii recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and NADPH | Pneumocystis jirovecii | 20 | ALA4219246 | cell-based format | Scientific Literature | |
12. | ALA4224046 | ADME | Inhibition of human recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and NADPH | Homo sapiens | 20 | ALA4219246 | cell-based format | Scientific Literature | |
13. | ALA4224047 | Toxicity | Selectivity ratio of IC50 for human recombinant DHFR to IC50 for Pneumocystis jirovecii recombinant DHFR | 20 | ALA4219246 | assay format | Scientific Literature |