# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA890447 | B | Inhibition of human procollagen C-proteinase expressed in CHO cells | Homo sapiens | 70 | cell-based format | Scientific Literature | ||
2. | ALA890448 | B | Inhibition of MMP1 | 5 | single protein format | Scientific Literature | |||
3. | ALA890449 | B | Inhibition of MMP2 | 12 | single protein format | Scientific Literature | |||
4. | ALA890454 | B | Inhibition of MMP1 at 10 uM | 5 | single protein format | Scientific Literature | |||
5. | ALA890455 | B | Inhibition of MMP2 at 10 uM | 8 | single protein format | Scientific Literature | |||
6. | ALA890460 | B | Inhibition of MMP1 at 100 uM | 5 | single protein format | Scientific Literature | |||
7. | ALA890461 | B | Inhibition of MMP2 at 100 uM | 8 | single protein format | Scientific Literature | |||
8. | ALA889323 | B | Inhibition of MMP1 at 30 uM | 5 | single protein format | Scientific Literature | |||
9. | ALA889324 | B | Inhibition of MMP2 at 30 uM | 8 | single protein format | Scientific Literature | |||
10. | ALA890477 | P | Lipophilicity, log D of the compound | 8 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA890478 | P | Dissociation constant, pKa of the compound | 6 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA890480 | F | Effect on transepidermal penetration in human cadaver skin using 14C-mannitol assessed as TED flux | Homo sapiens | 9 | tissue-based format | Scientific Literature | ||
13. | ALA890481 | P | Dissociation constant, pKa in aqueous propylene glycol | 1 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA890482 | P | Solubility in phosphate buffer at pH 4.8 | 2 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA890484 | P | Solubility in phosphate buffer at pH 3.8 | 1 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA890485 | P | Solubility in phosphate buffer at pH 7.5 | 1 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA3743608 | B | Inhibition of recombinant Brugia malayi DPY-31 astacin domain expressed in Escherichia coli using Suc-Ala-Ala-Ala-pNA as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by microplate reader assay | Brugia malayi | 5 | assay format | Scientific Literature | ||
18. | ALA3743609 | B | Inhibition of recombinant Teladorsagia circumcincta DPY-31 astacin domain expressed in Escherichia coli using Suc-Ala-Ala-Ala-pNA as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by microplate reader assay | Teladorsagia circumcincta | 5 | assay format | Scientific Literature |