# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA631418 | P | Calculated partition coefficient (clogP) | 27 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA678910 | B | Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 | 27 | protein complex format | Scientific Literature | |||
3. | ALA678911 | B | Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 | 27 | protein complex format | Scientific Literature | |||
4. | ALA722977 | F | Hypnotic activity was measured as dose which causes loss of righting reflex for a minimum period of 30s in 50% of mice; Range is 80-100 | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA726035 | T | Acute toxicity measured as median lethal dose in mice | Mus musculus | 28 | organism-based format | Scientific Literature | ||
6. | ALA858286 | F | Loss of righting reflex (LORR) in tadpoles was determined for anesthetic activity | frog | 26 | organism-based format | Scientific Literature | ||
7. | ALA914538 | F | Activity against caspase-mediated apoptosis in mouse L1210 cells | Mus musculus | 52 | cell-based format | Scientific Literature | ||
8. | ALA914539 | A | Cytotoxicity against mouse L1210 cells | Mus musculus | 96 | cell-based format | Scientific Literature | ||
9. | ALA956074 | B | Inhibition of human erythrocyte CA1 esterase activity using 4-nitrophenyl acetate substrate | Homo sapiens | 11 | single protein format | Scientific Literature | ||
10. | ALA956075 | B | Inhibition of human erythrocyte CA2 esterase activity using 4-nitrophenyl acetate substrate | Homo sapiens | 11 | single protein format | Scientific Literature | ||
11. | ALA4219940 | B | Positive allosteric modulation of human GlyRalpha3beta expressed in CHO cells assessed as potentiation of EC20 glycine-induced response at 5.9 uM by fluorescence based HTS assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
12. | ALA4219941 | B | Positive allosteric modulation of human GlyRalpha3beta expressed in CHO cells assessed as potentiation of EC20 glycine-induced ion flux at 10 uM by HT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
13. | ALA4219942 | B | Positive allosteric modulation of human GlyRalpha3beta expressed in CHO cells assessed as potentiation of EC20 glycine-induced ion flux by HT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
14. | ALA4219943 | B | Positive allosteric modulation of human GlyRalpha3beta expressed in CHO cells assessed as potentiation of EC5 to EC10 glycine-induced response at 10 uM by manual patch clamp assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
15. | ALA4219948 | B | Allosteric modulation of GlyRalpha3 in VGAT::ChR2 BAC transgenic mouse lumbar spinal cord slices assessed as increase in decay time constants of light-evoked Gly-IPSC at 100 uM by Whole cell patch clamp method | Mus musculus | 1 | assay format | Scientific Literature | ||
16. | ALA4219949 | B | Allosteric modulation of zymosan-A treated GlyRalpha3 in VGAT::ChR2 BAC transgenic mouse lumbar spinal cord slices assessed as increase in decay time constants of light-evoked Gly-IPSC at 100 uM by Whole cell patch clamp method | Mus musculus | 1 | assay format | Scientific Literature | ||
17. | ALA4219950 | F | Analgesic activity in zymosan-A induced inflammation mouse model assessed as reduction in mechanical hyperalgesia | Mus musculus | 1 | organism-based format | Scientific Literature | ||
18. | ALA4219951 | F | Analgesic activity in zymosan-A induced inflammation GlyR3 knock out mouse model assessed as reduction in mechanical hyperalgesia | Mus musculus | 1 | organism-based format | Scientific Literature |