| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1803355 | B | Inhibition of Hsp90 interaction with [35S]His-tagged HRI K199R mutant in reticulocyte lysate assessed as coadsorbed Hsp90 at 400 uM after 40 mins by SDS-PAGE and Western blot analysis | 1 | assay format | Scientific Literature | |||
| 2. | ALA1803502 | B | Inhibition of Hsp70 interaction with [35S]His-tagged HRI K199R mutant in reticulocyte lysate assessed as coadsorbed Hsp70 at 400 uM after 40 mins by SDS-PAGE and Western blot analysis | 1 | assay format | Scientific Literature | |||
| 3. | ALA1803503 | B | Inhibition of Cdc37 interaction with [35S]His-tagged HRI K199R mutant in reticulocyte lysate assessed as coadsorbed Cdc37 at 400 uM after 40 mins by SDS-PAGE and Western blot analysis | 1 | assay format | Scientific Literature | |||
| 4. | ALA1803599 | B | Inhibition of Hsp90-mediated [35S]His-tagged HRI maturation in heme-deficient reticulocyte lysate at 400 uM after 45 mins by SDS-PAGE and autoradiography | 1 | assay format | Scientific Literature | |||
| 5. | ALA1803605 | B | Effect on [35S]His-tagged HRI stability in heme-deficient reticulocyte lysate assessed as loss of [35S]His-tagged HRI at 400 uM after 45 mins by SDS-PAGE and autoradiography | 1 | assay format | Scientific Literature | |||
| 6. | ALA1798236 | F | Antiproliferative activity against human SKBR3 cells expressing HER2 after 72 hrs by MTS/PMS assay | Homo sapiens | 124 | cell-based format | Scientific Literature | ||
| 7. | ALA1825257 | F | Antiproliferative activity against human SKBR3 cells after 72 hrs by MTS/PMS assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 8. | ALA1825258 | F | Antiproliferative activity against human MCF7 cells after 72 hrs by MTS/PMS assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 9. | ALA889766 | F | Antiproliferative activity against human estrogen receptor positive MCF7 cells after 72 hrs | Homo sapiens | 66 | cell-based format | Scientific Literature | ||
| 10. | ALA889767 | F | Antiproliferative activity against human estrogen receptor negative SKBr3 cells overexpressing Her2 after 72 hrs | Homo sapiens | 66 | cell-based format | Scientific Literature | ||
| 11. | ALA2166270 | B | Inhibition of electric eel AChE at 2 mg/ml by Ellman's method | Electrophorus electricus | 500 | single protein format | Scientific Literature | ||
| 12. | ALA2166271 | B | Inhibition of horse BChE at 2 mg/ml by Ellman's method | Equus caballus | 500 | single protein format | Scientific Literature | ||
| 13. | ALA2216563 | F | Antibacterial activity against ciprofloxacin-resistant Staphylococcus aureus MB 5786 (R35) | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 14. | ALA2216564 | F | Antibacterial activity against ciprofloxacin-resistant Staphylococcus aureus MB 5785 (R34) | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 15. | ALA2216565 | F | Antibacterial activity against coumermycin A1-resistant Staphylococcus aureus MB 5957/H7 harboring GyrB Gln136Glu, Ile175Thr, Leu455Ile mutant | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 16. | ALA2216566 | F | Antibacterial activity against novobiocin-resistant Staphylococcus aureus MB 5957/A8 harboring GyrB ASP89Gly mutant | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 17. | ALA2216567 | F | Antibacterial activity against wild type Staphylococcus aureus MB 5957 | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 18. | ALA3107698 | B | Inhibition of Hsp90 in human HeLa cells assessed as downregulation of FKBP52 protein level at 50 uM after 30 hours by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3107699 | B | Inhibition of Hsp90 in human HeLa cells assessed as upregulation of glucocorticoid receptor protein level at 50 uM after 30 hours by Western blotting analysis relative to DMSO-treated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3107700 | B | Inhibition of Hsp90 in human HeLa cells assessed as change in FKBP51 protein level at 50 uM after 30 hours by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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