# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA942022 | B | Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assay | Homo sapiens | 27 | cell membrane format | Scientific Literature | ||
2. | ALA905955 | P | Aqueous solubility at pH 6.5 | 6 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA905956 | P | Distribution coefficient, log D of the compound | 6 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA905958 | F | Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTP-gamma-S binding assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
5. | ALA905959 | A | Clearance in mouse liver microsomes at 0.5 uM | Mus musculus | 6 | organism-based format | Scientific Literature | ||
6. | ALA905960 | A | Clearance in mouse at 1 mg/kg, iv | Mus musculus | 6 | organism-based format | Scientific Literature | ||
7. | ALA5257197 | B | Antagonist activity at mouse CXCR3 assessed as reduction in CXCL11 induced calcium flux by [35S]GTPgammaS binding assay | Mus musculus | 2 | single protein format | Scientific Literature | ||
8. | ALA5257198 | B | Antagonist activity at human CXCR3 assessed as reduction in CXCL11 induced calcium flux by [35S]GTPgammaS binding assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
9. | ALA5257203 | P | Solubility of compound | 10 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA5257230 | P | Lipophilicity, logD of compound at pH 7.4 | 5 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA5257231 | A | Intrinsic clearance in mouse liver microsomes | Mus musculus | 5 | microsome format | Scientific Literature |