# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA643700 | B | Antilog of the difference between pD2 of Alpha-2 adrenergic receptor and pD2 of Alpha-1 adrenergic receptor | 8 | protein format | Scientific Literature | |||
2. | ALA643027 | B | pD2 is -log ED50 required to produce 50% inhibition of the twitch response in rat vas deferens (intrinsic activity in presence of clonidine) for Alpha-2 adrenergic receptor | 6 | tissue-based format | Scientific Literature | |||
3. | ALA640225 | B | Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat cortex membrane | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
4. | ALA643867 | B | Inhibition of Alpha-1 adrenergic receptor twitch response in rat vas deferens in presence of cirazoline, pD2 is -log ED50 | Rattus norvegicus | 12 | tissue-based format | Scientific Literature | ||
5. | ALA649811 | B | Relative binding affinity for Alpha-2 adrenergic receptor and I2 imidazoline binding site (Antilog of the difference between pKi) | 13 | assay format | Scientific Literature | |||
6. | ALA841870 | B | Displacement of [3H]idazoxan from imidazoline receptor I-2 binding sites in rabbit kidney membrane | Oryctolagus cuniculus | 13 | cell membrane format | Scientific Literature | ||
7. | ALA895077 | B | Displacement of [3H]RX 821002 from human adrenergic alpha2A receptor expressed in CHO cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
8. | ALA895078 | B | Displacement of [3H]RX 821002 from human adrenergic alpha-2B receptor expressed in CHO cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
9. | ALA895079 | B | Displacement of [3H]RX 821002 from human adrenergic Alpha-2C receptor expressed in CHO cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
10. | ALA895080 | F | Agonistic potency at human adrenergic alpha-2A receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
11. | ALA895081 | F | Agonistic potency at human adrenergic alpha-2B receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
12. | ALA895082 | F | Agonistic potency at human adrenergic Alpha-2C receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
13. | ALA895083 | F | Intrinsic activity at human adrenergic alpha-2A receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation relative to (-)-noradrenaline | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
14. | ALA895084 | F | Intrinsic activity at human adrenergic alpha2B receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation relative to (-)- noradrenaline | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
15. | ALA895085 | F | Intrinsic activity at human adrenergic Alpha-2C receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation relative to (-)- noradrenaline | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
16. | ALA1285950 | B | Displacement of [3H]RX821002 from human alpha2A adrenoceptor expressed in CHO cells | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
17. | ALA1285951 | F | Agonist activity at human alpha2A adrenoceptor expressed in CHO cells assessed as induction of extracellular acidification by microphysiometry | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
18. | ALA1285952 | F | Agonist activity at human alpha2A adrenoceptor expressed in CHO cells assessed as induction of extracellular acidification by microphysiometry relative to (-)noradrenaline | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
19. | ALA1285954 | B | Displacement of [3H]RX821002 from human alpha2B adrenoceptor expressed in CHO cells | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
20. | ALA1286048 | F | Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as induction of extracellular acidification by microphysiometry | Homo sapiens | 14 | cell-based format | Scientific Literature |