| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA894930 | B | Inhibition of human recombinant soluble epoxide hydrolase | Homo sapiens | 49 | ALA1148702 | single protein format | Scientific Literature | |
| 2. | ALA894932 | A | Metabolic stability in human liver microsomes | Homo sapiens | 28 | ALA1148702 | microsome format | Scientific Literature | |
| 3. | ALA894933 | P | Solubility in sodium phosphate buffer at pH 7.4 | 28 | ALA1148702 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA894934 | B | Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescent assay | Mus musculus | 4 | ALA1148702 | single protein format | Scientific Literature | |
| 5. | ALA894935 | B | Inhibition of rat recombinant soluble epoxide hydrolase by fluorescent assay | Rattus norvegicus | 4 | ALA1148702 | single protein format | Scientific Literature | |
| 6. | ALA894936 | B | Inhibition of hamster soluble epoxide hydrolase by radioactive assay | Cricetinae | 4 | ALA1148702 | assay format | Scientific Literature | |
| 7. | ALA894937 | B | Inhibition of cat soluble epoxide hydrolase by radioactive assay | Felis catus | 4 | ALA1148702 | assay format | Scientific Literature | |
| 8. | ALA894938 | B | Inhibition of dog soluble epoxide hydrolase by radioactive assay | Canis lupus familiaris | 4 | ALA1148702 | assay format | Scientific Literature | |
| 9. | ALA894939 | B | Inhibition of human sEH by fluorescent assay | Homo sapiens | 4 | ALA1148702 | single protein format | Scientific Literature | |
| 10. | ALA894940 | A | AUC in in dog at 0.3 mg/kg, po | Canis lupus familiaris | 4 | ALA1148702 | organism-based format | Scientific Literature | |
| 11. | ALA894941 | A | Bioavailability in dog at 0.3 mg/kg, iv | Canis lupus familiaris | 1 | ALA1148702 | organism-based format | Scientific Literature | |
| 12. | ALA894942 | A | Bioavailability in dog at 0.3 mg/kg, po | Canis lupus familiaris | 1 | ALA1148702 | organism-based format | Scientific Literature | |
| 13. | ALA894931 | F | Reduction of LPS-induced blood pressure mouse C57BL/6 at 1 mg/kg, po | Mus musculus | 1 | ALA1148702 | organism-based format | Scientific Literature | |
| 14. | ALA894944 | F | Reduction of LPS-induced blood pressure mouse C57BL/6 at 0.5 mg/kg, po | Mus musculus | 1 | ALA1148702 | organism-based format | Scientific Literature | |
| 15. | ALA894945 | A | Tmax in dog at 0.3 mg/kg, po or 0.3 mg/kg, iv | Canis lupus familiaris | 1 | ALA1148702 | organism-based format | Scientific Literature | |
| 16. | ALA894946 | A | Half life in dog at 0.3 mg/kg, po or 0.3 mg/kg, iv | Canis lupus familiaris | 1 | ALA1148702 | organism-based format | Scientific Literature | |
| 17. | ALA1768319 | B | Inhibition of ovine COX-1 at 100 uM after 2 mins by fluorescence assay | Ovis aries | 24 | ALA1765073 | single protein format | Scientific Literature | |
| 18. | ALA1768320 | B | Inhibition of human recombinant COX-2 after 2 mins by fluorescence assay | Homo sapiens | 24 | ALA1765073 | single protein format | Scientific Literature | |
| 19. | ALA1768321 | B | Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assay | Homo sapiens | 24 | ALA1765073 | single protein format | Scientific Literature | |
| 20. | ALA1768326 | F | Antiallodynic activity in Sprague-Dawley rat von Frey hair mechanically-stimulated neuropathic pain model assessed as reversal of LPS-induced decrease in paw withdrawal latency at 10 mg/kg, sc administered 60 mins before LPS challenge | Rattus norvegicus | 3 | ALA1765073 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!