# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA894332 | F | Inhibition of CXCL8-induced cell migration in human PMN cells at 0.01 uM by chemotaxis assay | Homo sapiens | 77 | cell-based format | Scientific Literature | ||
2. | ALA894327 | F | Inhibition of CXCL1-induced cell migration in human PMN cells at 0.01 uM by chemotaxis assay | Homo sapiens | 78 | cell-based format | Scientific Literature | ||
3. | ALA2026801 | B | Inhibition of CXCR2 in human polymorphonucleate cells assessed as inhibition of CXCL1-induced chemotaxis at 10'-8 M incubated for 15 mins prior to CXCL1-induction measured after 45 mins | Homo sapiens | 22 | assay format | Scientific Literature | ||
4. | ALA2026802 | B | Inhibition of CXCR1/2 in human polymorphonucleate cells assessed as inhibition of CXCL8-induced chemotaxis at 10'-8 M incubated for 15 mins prior to CXCL8-induction measured after 45 mins | Homo sapiens | 22 | assay format | Scientific Literature | ||
5. | ALA2025043 | P | Chemical stability of the compound assessed as compound remaining at pH 7.4 after 2 hrs | 4 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA2025044 | A | Half life in iv dosed rat plasma | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
7. | ALA2025045 | A | Metabolic stability in rat liver microsomes assessed as compound remaining at 1 uM preincubated for 10 mins measured after 30 mins | Rattus norvegicus | 9 | microsome format | Scientific Literature | ||
8. | ALA2025046 | A | Metabolic stability in rat plasma assessed as compound remaining at 1 uM after 1 hr | Rattus norvegicus | 7 | cell-free format | Scientific Literature |