#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA895648	B	Displacement of [125I]IABN from human dopamine D2 receptor expressed in HEK293 cells	Homo sapiens	23		cell-based format	Scientific Literature
2.	ALA894567	B	Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells	Homo sapiens	23		cell-based format	Scientific Literature
3.	ALA895647	B	Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cells	Homo sapiens	23		cell-based format	Scientific Literature
4.	ALA895649	B	Selectivity for human dopamine D3 receptor over human dopamine D2 receptor	Homo sapiens	23		protein format	Scientific Literature
5.	ALA895651	F	Antagonist activity at human dopamine D2 receptor expressed in HEK293 cells by mitogenesis assay	Homo sapiens	16		cell-based format	Scientific Literature
6.	ALA895652	F	Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assay	Homo sapiens	13		cell-based format	Scientific Literature
7.	ALA895655	B	Binding affinity to human 5HT1A receptor	Homo sapiens	20		single protein format	Scientific Literature
8.	ALA895656	B	Binding affinity to human 5HT2A receptor	Homo sapiens	20		single protein format	Scientific Literature
9.	ALA895657	B	Binding affinity to human 5HT2C receptor	Homo sapiens	20		single protein format	Scientific Literature
10.	ALA895658	B	Selectivity for human dopamine D3 receptor over human 5HT1A receptor	Homo sapiens	20		assay format	Scientific Literature
11.	ALA895659	B	Selectivity for human dopamine D3 receptor over human 5HT2A receptor	Homo sapiens	20		assay format	Scientific Literature
12.	ALA895660	B	Selectivity for human dopamine D3 receptor over human 5HT2C receptor	Homo sapiens	20		assay format	Scientific Literature
13.	ALA3705175	B	Functional Assay: To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), CHOp-cells (human receptor) were seeded in a 96-well plate at a concentration of 5,000 cells/well. The cells were incubated at 37C. in alpha -MEM with 10% FBS, 0.05% penicillin-streptomycin, and 200 ug/mL of G418. After 48 hours, the cells were rinsed twice with serum-free alpha -MEM and incubated for 24 hours at 37 C. In the functional assay for agonism, the medium was removed and replaced with 90 ul of serum-free alpha -MEM and 10 ul of test compound in sterile water; in the antagonist assay, the test compound was diluted in sterile water plus 30 nM quinpirole. After another 24-hour incubation at 37 C., 0.25 uCi of [3H]thymidine was added to each well and the plates were further incubated for 2 hours at 37 C. The cells were then trypsinized, and the plates were filtered and counted as usual in the art.	Homo sapiens	8		assay format	BindingDB Database
14.	ALA3705176	B	Binding Assay: Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. Synapse 38:438-439 (2000). These papers describe radioactively labeled dopamine receptor selective ligands binding with picomolar affinity and nonselectivity to D2 and D3 dopamine receptors expressed in Sf9 and HEK 293 cells. 125I-IABN binds with 7- to 10-fold lower affinity to human D4.4 dopamine receptors expressed in HEK 293 cells. Dissociation constants (Kd) calculated from kinetic experiments were found to be in agreement with equilibrium Kd values obtained from saturation binding studies. Saturation plots of the binding of 125I-IABN with rat caudate membrane preparations were monophasic and exhibited low nonspecific binding.	Homo sapiens	29		cell-based format	BindingDB Database