# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA900718 | B | Inhibition of human recombinant MAOA expressed in Pichia pastoris | Homo sapiens | 3 | assay format | Scientific Literature | ||
2. | ALA900719 | B | Inhibition of human recombinant MAOB expressed in Pichia pastoris | Homo sapiens | 3 | assay format | Scientific Literature | ||
3. | ALA899613 | B | Selectivity for human recombinant MAOB over human recombinant MAOA | Homo sapiens | 1 | assay format | Scientific Literature | ||
4. | ALA895226 | B | Inhibition of rat brain mitochondria MAOA by radioenzymatic assay | Rattus norvegicus | 17 | mitochondrion format | Scientific Literature | ||
5. | ALA895227 | B | Inhibition of rat brain mitochondria MAOB by radioenzymatic assay | Rattus norvegicus | 22 | mitochondrion format | Scientific Literature | ||
6. | ALA895228 | B | Selectivity index, ratio of IC50 for rat brain mitochondria MAOA to IC50 for rat brain mitochondria MAOB | Rattus norvegicus | 25 | mitochondrion format | Scientific Literature | ||
7. | ALA1059215 | B | Inhibition of MAOB | 22 | single protein format | Scientific Literature | |||
8. | ALA1107401 | B | Inhibition of tetrodotoxin-sensitive Na+ channel by patch-clamp electrophysiology | 1 | single protein format | Scientific Literature | |||
9. | ALA1107402 | B | Inhibition of tetrodotoxin-sensitive Na+ channel at -50 mV membrane holding potential by patch-clamp electrophysiology | 1 | assay format | Scientific Literature | |||
10. | ALA1107408 | F | Anticonvulsant activity in ip dosed albino mouse assessed as inhibition of maximal electroshock-induced seizures | Mus musculus | 4 | organism-based format | Scientific Literature | ||
11. | ALA1107414 | T | Toxicity in ip dosed albino mouse by rotarod test | Mus musculus | 4 | organism-based format | Scientific Literature | ||
12. | ALA1107415 | F | Protective index, ratio of TD50 for albino mouse to anticonvulsant ED50 for albino mouse | Mus musculus | 13 | organism-based format | Scientific Literature | ||
13. | ALA1109099 | F | Anticonvulsant activity in albino mouse assessed as protection against subcutaneous metrazole-induced seizures up to 300 mg/kg, ip after 0.5 hrs | Mus musculus | 14 | organism-based format | Scientific Literature | ||
14. | ALA1109100 | F | Anticonvulsant activity in albino mouse assessed as protection against subcutaneous metrazole-induced seizures up to 300 mg/kg, ip after 4 hrs | Mus musculus | 14 | organism-based format | Scientific Literature | ||
15. | ALA1109109 | F | Anticonvulsant activity in ip dosed albino mouse assessed as protection against subcutaneous metrazole-induced seizures | Mus musculus | 3 | organism-based format | Scientific Literature | ||
16. | ALA2382553 | B | Reversible inhibition of human MAO-B using p-tyramine as substrate at IC80 incubated for 22 mins followed by substrate addition measured for 5 hrs by fluorescence assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
17. | ALA2382554 | B | Selectivity ratio of IC50 for MAO-B in mitochondria-enriched Sprague-Dawley rat liver fractions to IC50 for recombinant human MAO-B | 30 | mitochondrion format | Scientific Literature | |||
18. | ALA2382555 | B | Inhibition of recombinant human MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate incubated for 30 mins prior to substrate addition measured for 45 mins by amplex red reagent-based microplate fluorescence reader analysis | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
19. | ALA2382556 | B | Inhibition of MAO-B in mitochondria-enriched Sprague-Dawley rat liver fractions using p-tyramine as substrate incubated for 30 mins prior to substrate addition measured for 45 mins by amplex red reagent-based microplate fluorescence reader analysis | Rattus norvegicus | 33 | mitochondrion format | Scientific Literature | ||
20. | ALA3095874 | B | Inhibition of human MAO-B | Homo sapiens | 59 | single protein format | Scientific Literature |