# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA895410 | B | Inhibition of self-induced amyloid beta (1-40) aggregation at 10 uM by thioflavin T based fluorometric assay | Homo sapiens | 35 | ALA1148814 | single protein format | Scientific Literature | |
2. | ALA895411 | B | Activity of NQO1 enzyme | Homo sapiens | 4 | ALA1148814 | single protein format | Scientific Literature | |
3. | ALA895412 | F | Antioxidant activity in human SHSY5Y cells overexpressing NQO1 assessed as increase in tert-butyl hydroperoxide evoked-intracellular ROS formation at 0.1 uM after 24 hrs relative to control | Homo sapiens | 3 | ALA1148814 | cell-based format | Scientific Literature | |
4. | ALA895413 | F | Antioxidant activity in human SHSY5Y cells overexpressing NQO1 assessed as increase in tert-butyl hydroperoxide evoked-intracellular ROS formation at 0.3 uM after 24 hrs relative to control | Homo sapiens | 3 | ALA1148814 | cell-based format | Scientific Literature | |
5. | ALA895414 | F | Antioxidant activity in human SHSY5Y cells overexpressing NQO1 assessed as increase in tert-butyl hydroperoxide evoked-intracellular ROS formation at 1 uM after 24 hrs relative to control | Homo sapiens | 3 | ALA1148814 | cell-based format | Scientific Literature | |
6. | ALA894351 | F | Antioxidant activity in human SHSY5Y cells overexpressing NQO1 assessed as increase in tert-butyl hydroperoxide evoked-intracellular ROS formation at 3 uM after 24 hrs relative to control | Homo sapiens | 3 | ALA1148814 | cell-based format | Scientific Literature | |
7. | ALA945890 | B | Inhibition of human AchE | Homo sapiens | 31 | ALA1141467 | single protein format | Scientific Literature | |
8. | ALA945901 | B | Inhibition of BACE1 | 1 | ALA1141467 | single protein format | Scientific Literature | ||
9. | ALA945902 | B | Inhibition of human AchE induced amyloid beta40 aggregation | Homo sapiens | 1 | ALA1141467 | single protein format | Scientific Literature | |
10. | ALA945903 | B | Inhibition of human AchE induced amyloid beta42 aggregation | Homo sapiens | 1 | ALA1141467 | single protein format | Scientific Literature | |
11. | ALA945893 | B | Binding affinity to NQQ1 | 1 | ALA1141467 | single protein format | Scientific Literature | ||
12. | ALA1058842 | B | Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman method | Homo sapiens | 4 | ALA1152360 | single protein format | Scientific Literature | |
13. | ALA1058843 | B | Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman method | Homo sapiens | 4 | ALA1152360 | single protein format | Scientific Literature | |
14. | ALA1058844 | B | Selectivity ratio of IC50 for human recombinant BchE to IC50 for human recombinant AChE | Homo sapiens | 4 | ALA1152360 | assay format | Scientific Literature | |
15. | ALA1058846 | B | Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assay | Homo sapiens | 4 | ALA1152360 | single protein format | Scientific Literature | |
16. | ALA1058847 | B | Inhibition of self-assembly of human amyloid beta (1-42) aggregation at 10 uM by thioflavin T-based fluorometric assay | Homo sapiens | 4 | ALA1152360 | single protein format | Scientific Literature | |
17. | ALA1037610 | B | Inhibition of human recombinant AChE by Ellman's method | Homo sapiens | 6 | ALA1154602 | single protein format | Scientific Literature | |
18. | ALA1037611 | B | Inhibition of human recombinant BChE by Ellman's method | Homo sapiens | 6 | ALA1154602 | single protein format | Scientific Literature | |
19. | ALA1217062 | B | Inhibition of AChE | 3 | ALA1212814 | single protein format | Scientific Literature | ||
20. | ALA1217063 | B | Inhibition of AChE-induced amyloid beta (1-40) aggregation | 2 | ALA1212814 | single protein format | Scientific Literature |