# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA895461 | F | Displacement of [35S]GTP-gamma-S from human cloned dopamine D3 receptor expressed in CHO cells after 30 mins | Homo sapiens | 42 | ALA1148818 | cell-based format | Scientific Literature | |
2. | ALA895462 | F | Displacement of [35S]GTP-gamma-S from human cloned dopamine D2 receptor expressed in CHO cells after 30 mins | Homo sapiens | 42 | ALA1148818 | cell-based format | Scientific Literature | |
3. | ALA895463 | F | Binding affinity to human histamine H1 receptor expressed in CHO cells by FLIPR assay | Homo sapiens | 42 | ALA1148818 | cell-based format | Scientific Literature | |
4. | ALA895464 | B | Displacement of [3H]dofetilide from hERG expressed in CHO cells | Homo sapiens | 42 | ALA1148818 | cell-based format | Scientific Literature | |
5. | ALA895468 | A | Volume of distribution in Sprague-Dawley rat | Rattus norvegicus | 4 | ALA1148818 | organism-based format | Scientific Literature | |
6. | ALA895471 | A | Inhibition of human cytochrome P450 at <10 uM | Homo sapiens | 1 | ALA1148818 | assay format | Scientific Literature | |
7. | ALA895472 | A | Intrinsic clearance in human liver microsome | Homo sapiens | 3 | ALA1148818 | microsome format | Scientific Literature | |
8. | ALA895473 | A | Blood clearance in Sprague-Dawley rat at 20 mg/kg after 30 mins | Rattus norvegicus | 1 | ALA1148818 | organism-based format | Scientific Literature | |
9. | ALA895474 | A | Bioavailability in Sprague-Dawley rat at 20 mg/kg after 30 mins | Rattus norvegicus | 1 | ALA1148818 | organism-based format | Scientific Literature | |
10. | ALA895475 | A | Volume of distribution in Sprague-Dawley rat at 20 mg/kg after 30 mins | Rattus norvegicus | 1 | ALA1148818 | organism-based format | Scientific Literature | |
11. | ALA895476 | A | Half life in Sprague-Dawley rat at 20 mg/kg after 30 mins | Rattus norvegicus | 1 | ALA1148818 | organism-based format | Scientific Literature | |
12. | ALA895477 | A | Ratio of drug level in blood to brain in Sprague-Dawley rat at 20 mg/kg after 30 mins | Rattus norvegicus | 1 | ALA1148818 | organism-based format | Scientific Literature | |
13. | ALA895478 | B | Binding affinity to hERG expressed in CHO cells by patch clamp assay | Homo sapiens | 2 | ALA1148818 | cell-based format | Scientific Literature | |
14. | ALA895479 | F | Effect on QT interval in iv dosed Hartley guinea pig after 15 mins | Cavia porcellus | 2 | ALA1148818 | organism-based format | Scientific Literature | |
15. | ALA895480 | A | Cmax in Sprague-Dawley rat at 20 mg/kg after 30 mins | Rattus norvegicus | 1 | ALA1148818 | organism-based format | Scientific Literature | |
16. | ALA895481 | A | Cmax in Hartley guinea pig at 25 mg/kg | Cavia porcellus | 1 | ALA1148818 | organism-based format | Scientific Literature | |
17. | ALA895482 | F | Displacement of [35S]GTP-gamma-S from human recombinant dopamine D3 receptor expressed in CHO cells after 30 mins at 10 uM | Homo sapiens | 1 | ALA1148818 | cell-based format | Scientific Literature | |
18. | ALA895483 | F | Displacement of [35S]GTPgammaS from human recombinant dopamine D2 receptor expressed in CHO cells after 30 mins at 10 uM | Homo sapiens | 1 | ALA1148818 | cell-based format | Scientific Literature | |
19. | ALA895484 | B | Displacement of [3H]FLB457 from human recombinant dopamine D3 receptor expressed in CHO cells after 45 mins | Homo sapiens | 1 | ALA1148818 | cell-based format | Scientific Literature | |
20. | ALA895485 | B | Binding affinity to human recombinant dopamine D2 | Homo sapiens | 1 | ALA1148818 | single protein format | Scientific Literature |