# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1913189 | B | Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol method | Canavalia ensiformis | 19 | single protein format | Scientific Literature | ||
2. | ALA891104 | B | Inhibition of pieris rapae Phenoloxidase | Pieris rapae | 57 | assay format | Scientific Literature | ||
3. | ALA1273026 | F | Inhibition of melanogenesis in mouse B16 cells at 10 uM | Mus musculus | 19 | cell-based format | Scientific Literature | ||
4. | ALA1273027 | F | Inhibition of melanogenesis in mouse B16 cells | Mus musculus | 19 | cell-based format | Scientific Literature | ||
5. | ALA3591431 | F | Larvicidal activity against Aedes aegypti L4 stage larvae assessed as induction of larval mortality incubated for 48 hrs | Aedes aegypti | 18 | organism-based format | Scientific Literature | ||
6. | ALA3591432 | A | Cytotoxicity against BALB/c mouse splenocytes assessed as reduction in cell viability incubated for 24 hrs by beta-radiation counting based [3H]-thymidine incorporation assay | Mus musculus | 17 | cell-based format | Scientific Literature | ||
7. | ALA3591434 | B | Inhibition of NBD-cholesterol binding to recombinant Aedes aegypti SCP-2 protein by fluorescence based assay | Aedes aegypti | 2 | single protein format | Scientific Literature | ||
8. | ALA4036442 | B | Inhibition of Agaricus bisporus tyrosinase assessed as reduction in diphenolase activity by measuring L-DOPA oxidation after 30 mins | Agaricus bisporus | 9 | assay format | Scientific Literature | ||
9. | ALA4036451 | B | Inhibition of Agaricus bisporus tyrosinase assessed as reduction in diphenolase activity by measuring apparent Km for L-DOPA oxidation at 1.6 mM after 30 mins by Lineweaver-Burk plot | Agaricus bisporus | 8 | assay format | Scientific Literature | ||
10. | ALA4036452 | B | Inhibition of Agaricus bisporus tyrosinase assessed as reduction in diphenolase activity by measuring Vmax for L-DOPA oxidation at 1.6 mM after 30 mins by Lineweaver-Burk plot | Agaricus bisporus | 8 | assay format | Scientific Literature | ||
11. | ALA4036453 | B | Uncompetitive mixed type inhibition of Agaricus bisporus tyrosinase assessed as reduction in diphenolase activity by measuring L-DOPA oxidation at 1.6 mM after 30 mins by Lineweaver-Burk plot | Agaricus bisporus | 2 | assay format | Scientific Literature | ||
12. | ALA4036457 | B | Inhibition of Agaricus bisporus tyrosinase assessed as reduction in diphenolase activity by measuring L-DOPA oxidation at 1.6 mM after 0 to 70 mins by UV-visible specroscopy | Agaricus bisporus | 7 | assay format | Scientific Literature | ||
13. | ALA4196378 | F | Antitrypanosomal activity against Trypanosoma brucei Lister 427 bloodstream form assessed as parasite growth inhibition at 50 uM after 72 hrs by SYBR Green assay relative to control | Trypanosoma brucei | 28 | organism-based format | Scientific Literature | ||
14. | ALA4196379 | F | Antileishmanial activity against Leishmania infantum amastigote form assessed as parasite growth inhibition at 50 uM after 72 hrs by steady-Glo reagent based assay relative to control | Leishmania infantum | 28 | organism-based format | Scientific Literature | ||
15. | ALA4196380 | F | Antitrypanosomal activity against Trypanosoma cruzi amastigote form infected in human U2OS cells assessed as parasite growth inhibition at 50 uM after 72 hrs relative to control | Trypanosoma cruzi | 42 | organism-based format | Scientific Literature | ||
16. | ALA4196384 | F | Antitrypanosomal activity against Trypanosoma brucei Lister 427 bloodstream form at 10 uM after 72 hrs by resazurin dye-based assay relative to control | Trypanosoma brucei | 28 | organism-based format | Scientific Literature | ||
17. | ALA4196385 | F | Potentiation of methotrexate-induced antitrypanosomal activity against Trypanosoma brucei Lister 427 bloodstream form at 10 uM after 72 hrs by resazurin dye-based assay relative to control | Trypanosoma brucei | 28 | organism-based format | Scientific Literature | ||
18. | ALA4196386 | A | Inhibition of human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cells at 10 uM incubated for 30 mins by luciferase assay relative to control | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
19. | ALA4196387 | F | Potentiation of methotrexate-induced antitrypanosomal activity against Trypanosoma brucei Lister 427 bloodstream form at 10 uM after 72 hrs by resazurin dye-based assay | Trypanosoma brucei | 28 | organism-based format | Scientific Literature | ||
20. | ALA4196392 | B | Inhibition of human ERG at 10 uM incubated for 2 hrs by fluorescence polarisation assay relative to control | Homo sapiens | 28 | single protein format | Scientific Literature |