# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA653904 | F | Average potency against CEM cells | Homo sapiens | 56 | cell-based format | Scientific Literature | ||
2. | ALA653782 | F | Inhibitory activity was tested against CEM cells | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
3. | ALA704364 | F | Average potency against L1210 cells | Mus musculus | 56 | cell-based format | Scientific Literature | ||
4. | ALA872509 | F | Inhibitory activity was tested against L1210 cells | Mus musculus | 57 | cell-based format | Scientific Literature | ||
5. | ALA729371 | F | Average potency against Molt4/C8cells | Homo sapiens | 56 | cell-based format | Scientific Literature | ||
6. | ALA729374 | F | Inhibitory activity was tested against Molt4/C8 cells | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
7. | ALA757906 | F | Inhibitory activity was tested against P388 cells | Mus musculus | 57 | cell-based format | Scientific Literature | ||
8. | ALA757448 | F | Average potency against P388 cells | Mus musculus | 56 | cell-based format | Scientific Literature | ||
9. | ALA3858834 | B | Inhibition of recombinant human MAO-A using kynuramine as substrate after 20 mins by fluorescence spectrophotometric analysis | Homo sapiens | 21 | single protein format | Scientific Literature | ||
10. | ALA3858835 | B | Inhibition of recombinant human MAO-B using kynuramine as substrate after 20 mins by fluorescence spectrophotometric analysis | Homo sapiens | 22 | single protein format | Scientific Literature | ||
11. | ALA3858837 | B | Selectivity index, ratio of IC50 for recombinant human MAO-A to IC50 for recombinant human MAO-B | Homo sapiens | 22 | assay format | Scientific Literature | ||
12. | ALA4034120 | F | Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation after 24 hrs by CMH2DCFDA probe-based fluorescence assay | Mus musculus | 63 | cell-based format | Scientific Literature | ||
13. | ALA4034123 | A | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 10 uM after 24 hrs by MTS assay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
14. | ALA4130991 | F | Inhibition of TNF-alpha-induced adhesion of BCECF-labeled human U937 cells to human HT-29 cells at 10 uM preincubated for 1 hr followed by TNF-alpha challenge measured after 3 hrs by fluorescence microscopic method relative to control | Homo sapiens | 59 | cell-based format | Scientific Literature | ||
15. | ALA4130993 | F | Inhibition of TNF-alpha-induced adhesion of BCECF-labeled human U937 cells to human HT-29 cells preincubated for 1 hr followed by TNF-alpha challenge measured after 3 hrs by fluorescence microscopic method | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
16. | ALA4130998 | F | Inhibition of TNF-alpha-induced MCP-1 expression in human HT-29 cells at 10 uM preincubated for 1 hr followed by TNF-alpha challenge measured after 3 hrs by Western blot analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
17. | ALA4131000 | F | Inhibition of TNF-alpha-induced NFkappa-B transcriptional activity in human HT-29 cells at 10 uM preincubated for 1 hr followed by TNF-alpha challenge measured after 3 hrs by dual luciferase reporter gene assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
18. | ALA4420888 | B | Inhibition of Dusp6 in (Tg(Dusp6:d2EGFP)pt6) transgenic Zebrafish assessed as activation of FGF signaling at 20 uM by d2EGFP fluorescence based assay | Danio rerio | 2 | single protein format | Patent Bioactivity Data | ||
19. | ALA4420918 | B | Inhibition of Dusp6 in (Tg(Dusp6:d2EGFP)pt6) transgenic Zebrafish assessed as activation of FGF signaling at 20 uM treated at 24 hours post fertilization and measured after 6 hrs post dose by d2EGFP fluorescence based assay relative to BCI | Danio rerio | 18 | single protein format | Patent Bioactivity Data | ||
20. | ALA4688062 | B | Inhibition of porcine pancreatic lipase type 2 | Sus scrofa | 4 | assay format | Scientific Literature |