| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA899634 | Functional | Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay | Homo sapiens | 27 | ALA1137460 | cell-based format | Scientific Literature | |
| 2. | ALA899636 | Functional | Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay | Homo sapiens | 27 | ALA1137460 | cell-based format | Scientific Literature | |
| 3. | ALA899641 | Functional | Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay in relative to niacin | Homo sapiens | 27 | ALA1137460 | cell-based format | Scientific Literature | |
| 4. | ALA924060 | Functional | Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test | Homo sapiens | 41 | ALA1140673 | assay format | Scientific Literature | |
| 5. | ALA784063 | Functional | G protein activation was measured by stimulation of [35S]GTP gamma-S binding to rat adipocyte membranes | Rattus norvegicus | 9 | ALA1145993 | organism-based format | Scientific Literature | |
| 6. | ALA777085 | Functional | Potency required for stimulation of [35S]GTP gamma-S binding to rat spleen was determined | Rattus norvegicus | 8 | ALA1145993 | organism-based format | Scientific Literature | |
| 7. | ALA794202 | Functional | Relative intrinsic activity in stimulation of [35S]GTP gamma-S binding to rat adipocyte was determined | Rattus norvegicus | 9 | ALA1145993 | organism-based format | Scientific Literature | |
| 8. | ALA794203 | Functional | Relative intrinsic activity in stimulation of [35S]GTP gamma-S binding to rat spleen was determined | Rattus norvegicus | 8 | ALA1145993 | organism-based format | Scientific Literature | |
| 9. | ALA1738312 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] | Homo sapiens | 55,525 | ALA1201862 | assay format | PubChem BioAssays | |
| 10. | ALA1737991 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] | Homo sapiens | 51,376 | ALA1201862 | assay format | PubChem BioAssays | |
| 11. | ALA1738442 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] | Homo sapiens | 90,358 | ALA1201862 | assay format | PubChem BioAssays | |
| 12. | ALA751847 | Binding | Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane. | Rattus norvegicus | 20 | ALA1145993 | cell membrane format | Scientific Literature | |
| 13. | ALA921658 | Functional | Agonist activity at GPR109A receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced intracellular cAMP production by Flashplate assay | 7 | ALA1147980 | cell-based format | Scientific Literature | ||
| 14. | ALA921659 | Functional | Agonist activity at GPR109A receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced intracellular cAMP production by Flashplate assay relative to nicotinic acid | 7 | ALA1147980 | cell-based format | Scientific Literature | ||
| 15. | ALA921661 | Functional | Reduction of free fatty acid level in ip dosed C57/BL6 mouse plasma after 10 mins | Mus musculus | 6 | ALA1147980 | organism-based format | Scientific Literature | |
| 16. | ALA921662 | Functional | Reduction of free fatty acid level in po dosed Sprague-Dawley rat plasma | Rattus norvegicus | 6 | ALA1147980 | organism-based format | Scientific Literature | |
| 17. | ALA921663 | Functional | Reduction of free fatty acid level in po dosed Sprague-Dawley rat plasma relative to baseline | Rattus norvegicus | 6 | ALA1147980 | organism-based format | Scientific Literature | |
| 18. | ALA921664 | ADME | Induction of flushing response in ip dosed C57/BL6 mouse | Mus musculus | 7 | ALA1147980 | organism-based format | Scientific Literature | |
| 19. | ALA921666 | Binding | Activation of GPR109A receptor in CHOK1 cells assessed as ERK1/2 MAP kinase activation by ELISA | 4 | ALA1147980 | cell-based format | Scientific Literature | ||
| 20. | ALA933837 | Binding | Induction of internalization of epitope-tagged GPR109A receptor expressed in COS7 cells at 10 uM after 30 mins | 4 | ALA1147980 | cell-based format | Scientific Literature |
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