# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA899634 | Functional | Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay | Homo sapiens | 27 | ALA1137460 | cell-based format | Scientific Literature | |
2. | ALA899636 | Functional | Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay | Homo sapiens | 27 | ALA1137460 | cell-based format | Scientific Literature | |
3. | ALA899641 | Functional | Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay in relative to niacin | Homo sapiens | 27 | ALA1137460 | cell-based format | Scientific Literature | |
4. | ALA924060 | Functional | Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test | Homo sapiens | 41 | ALA1140673 | assay format | Scientific Literature | |
5. | ALA784063 | Functional | G protein activation was measured by stimulation of [35S]GTP gamma-S binding to rat adipocyte membranes | Rattus norvegicus | 9 | ALA1145993 | organism-based format | Scientific Literature | |
6. | ALA777085 | Functional | Potency required for stimulation of [35S]GTP gamma-S binding to rat spleen was determined | Rattus norvegicus | 8 | ALA1145993 | organism-based format | Scientific Literature | |
7. | ALA794202 | Functional | Relative intrinsic activity in stimulation of [35S]GTP gamma-S binding to rat adipocyte was determined | Rattus norvegicus | 9 | ALA1145993 | organism-based format | Scientific Literature | |
8. | ALA794203 | Functional | Relative intrinsic activity in stimulation of [35S]GTP gamma-S binding to rat spleen was determined | Rattus norvegicus | 8 | ALA1145993 | organism-based format | Scientific Literature | |
9. | ALA751847 | Binding | Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane. | Rattus norvegicus | 20 | ALA1145993 | cell membrane format | Scientific Literature | |
10. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
11. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 |