| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4335475 | A | Cytotoxicity against human RD cells assessed as cell survival at <5 uM after 24 hrs by CCK8 assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4335476 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in human RD cells assessed as inhibition of virus-induced cytopathic effect at 0.08 uM/L preincubated with viral suspension for 2 hrs followed by cell addition and measured after 24 hrs by CCK-8 assay relative to control | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4335477 | A | Cytotoxicity against human RD cells assessed as reduction in cell viability after 12 hrs by CCK8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4335478 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in human RD cells assessed as inhibition of virus-induced cytopathic effect preincubated with viral suspension for 2 hrs followed by cell addition and measured after 24 hrs by CCK-8 assay | Coxsackievirus A16 | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4335479 | T | Selectivity index, ratio of CC50 for cytotoxicity against human RD cells to EC50 for antiviral activity against Coxsackievirus A16 TA271 infected in human RD cells | 2 | cell-based format | Scientific Literature | |||
| 6. | ALA4335480 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells assessed as inhibition of viral adsorption/viral entry by measuring increase in cell viability at 0.08 uM/L after 1 hr by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4335481 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at preinfection stage assessed as appearance of cell shrinkage at 0.08 uM/L preincubated with cells for 3 hrs followed by viral infection and measured after 1 hr by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4335482 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at preinfection stage assessed as appearance of rounded cells at 0.08 uM/L preincubated with cells for 3 hrs followed by viral infection and measured after 1 hr by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4335483 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at preinfection stage assessed as cell detachment at 0.08 uM/L preincubated with cells for 3 hrs followed by viral infection and measured after 1 hr by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4335484 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at preinfection stage assessed as cell fragmentation at 0.08 uM/L preincubated with cells for 3 hrs followed by viral infection and measured after 1 hr by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4335485 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at preinfection stage assessed as increase in intracytoplasmic granules at 0.08 uM/L preincubated with cells for 3 hrs followed by viral infection and measured after 1 hr by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4335486 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at replication stage assessed as appearance of cell shrinkage at 0.08 uM/L 1 hr post-infection viral inoculum was removed and cells incubated with medium containing compound and measured after 5 hrs by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4335487 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at replication stage assessed as appearance of rounded cells at 0.08 uM/L 1 hr post-infection viral inoculum was removed and cells incubated with medium containing compound and measured after 5 hrs by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4335488 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at replication stage assessed as cell detachment at 0.08 uM/L 1 hr post-infection viral inoculum was removed and cells incubated with medium containing compound and measured after 5 hrs by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4335489 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at replication stage assessed as cell fragmentation at 0.08 uM/L 1 hr post-infection viral inoculum was removed and cells incubated with medium containing compound and measured after 5 hrs by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4335490 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at replication stage assessed as increase in intracytoplasmic granules at 0.08 uM/L 1 hr post-infection viral inoculum was removed and cells incubated with medium containing compound and measured after 5 hrs by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4335491 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at release stage assessed as appearance of cell shrinkage at 0.08 uM/L preincubated with cells for 1 hr followed by replacement of fresh medium containing compounds after 5 hrs post infection and further incubated for 16 hrs post infection by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4335492 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at release stage assessed as appearance of rounded cells at 0.08 uM/L preincubated with cells for 1 hr followed by replacement of fresh medium containing compounds after 5 hrs post infection and further incubated for 16 hrs post infection by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4335493 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at release stage assessed as cell detachment at 0.08 uM/L preincubated with cells for 1 hr followed by replacement of fresh medium containing compounds after 5 hrs post infection and further incubated for 16 hrs post infection by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4335494 | F | Antiviral activity against Coxsackievirus A16 TA271 infected in RD cells at release stage assessed as cell fragmentation at 0.08 uM/L preincubated with cells for 1 hr followed by replacement of fresh medium containing compounds after 5 hrs post infection and further incubated for 16 hrs post infection by inverted microscopic analysis | Coxsackievirus A16 | 1 | cell-based format | Scientific Literature |
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