| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1827362 | B | Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assay | Homo sapiens | 234 | single protein format | Scientific Literature | ||
| 2. | ALA1827363 | B | Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assay | Homo sapiens | 234 | single protein format | Scientific Literature | ||
| 3. | ALA1827364 | P | Lipophilicity, log D of the compound | 234 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA900873 | B | Displacement of [3H]-N-alpha methyl histamine from human H3 receptor expressed in C6 cells | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA900871 | B | Displacement of [3H]-N-alpha methyl histamine from rat H3 receptor expressed in C6 cells | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA900874 | F | Antagonist activity at human histamine H3 receptor expressed with Galphaq/i5 in HEL239 cells assessed as reduction of RAMH-induced intracellular calcium | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA900875 | F | Antagonist activity at human histamine H3 receptor expressed in HEK239 cells assessed as inhibition of RAMH-stimulated [35S]GTP-gamma-S binding | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA900876 | F | Antagonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as inhibition of RAMH-stimulated [35S]GTP-gamma-S binding | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA900877 | F | Agonist activity at human histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTP-gamma-S binding | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 10. | ALA900878 | F | Agonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTP-gamma-S binding | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA900879 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 12. | ALA900880 | A | Volume of distribution in rat at 1 mg/kg, iv | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 13. | ALA900881 | A | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 14. | ALA900882 | A | Oral bioavailability in rat at 1 mg/kg | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 15. | ALA900883 | A | Drug level in mouse brain at 1 mg/kg, ip | Mus musculus | 6 | organism-based format | Scientific Literature | ||
| 16. | ALA900884 | A | Ratio of drug level in brain to blood in mouse at 1 mg/kg, ip | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 17. | ALA900885 | A | Drug level in rat brain at 1 mg/kg, iv | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 18. | ALA900872 | A | Ratio of drug level in brain to blood in rat at 1 mg/kg, iv | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 19. | ALA900886 | A | Protein binding in dog plasma | Canis lupus familiaris | 7 | cell-free format | Scientific Literature | ||
| 20. | ALA900887 | A | Protein binding in human plasma | Homo sapiens | 7 | cell-free format | Scientific Literature |
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