| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA902036 | F | Bone mineral affinity on hydroxyaptite assessed as retention time by chromatography | 10 | assay format | Scientific Literature | |||
| 2. | ALA902037 | B | Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3) | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 3. | ALA902038 | A | Reduction of viability of mouse J744 cells after 48 hrs | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 4. | ALA902040 | B | Inhibition of RGGT | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 5. | ALA902041 | B | Inhibition of RGGT mediated Rab11 prenylation in J744 cells | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA3424031 | B | Inhibition of recombinant FDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using GPP and [14C]IPP as substrate treated with enzyme for 10 mins prior to substrate challenge for 30 mins by liquid scintillation counting analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 7. | ALA3424032 | B | Inhibition of recombinant GGTase 2 (unknown origin) using recombinant Rab1A and [3H]GGPP as substrate after 20 mins in presence of recombinant REP-2 by liquid scintillation counting analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 8. | ALA3424033 | B | Inhibition of GGTase 1 in human RPMI8226 cells assessed as unmodified Rap1a accumulation at 5 mM incubated for 48 hrs by immunoblot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA3424034 | B | Inhibition of GGTase 2 in human RPMI8226 cells assessed as reduction in membrane bound Rab6 protein at 5 mM incubated for 48 hrs by immunoblot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3424037 | F | Induction of apoptosis in human RPMI8226 cells assessed as increase in PARP cleavage at 5 mM incubated for 48 hrs by immunoblot method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3424038 | F | Induction of apoptosis in human RPMI8226 cells assessed as increase in caspase-3 cleavage at 5 mM incubated for 48 hrs by immunoblot method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA3424039 | F | Induction of endoplasmic reticulum stress in human RPMI8226 cells assessed as increase in calnexin cleavage at 5 mM incubated for 48 hrs by immunoblot method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA3424040 | B | Inhibition of GGTase 2 in human RPMI8226 cells assessed as disruption of monoclonal protein trafficking by measuring accumulation of intracellular lambda light chain at 5 mM incubated for 48 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature |
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