# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA901965 | Binding | Channel opening activity at human bladder Kir6.2 channel containing SUR2B expressed in L cells by FLIPR assay | Homo sapiens | 57 | ALA1138291 | cell-based format | Scientific Literature | |
2. | ALA901967 | Functional | Inhibition of unstable spontaneous bladder contractions in Landrace/Yorkshire pig bladder instability model | Sus scrofa | 1 | ALA1138291 | organism-based format | Scientific Literature | |
3. | ALA901968 | Functional | Reduction of unstable spontaneous bladder contractions in Landrace/Yorkshire pig bladder instability model at 0.3 mg/kg, iv | Sus scrofa | 1 | ALA1138291 | organism-based format | Scientific Literature | |
4. | ALA901969 | Functional | Reduction of unstable spontaneous bladder contractions in Landrace/Yorkshire pig bladder instability model at 1 mg/kg, iv | Sus scrofa | 1 | ALA1138291 | organism-based format | Scientific Literature | |
5. | ALA901970 | Functional | Reduction of blood pressure in pig at 0.3 mg/kg, iv | Sus scrofa | 1 | ALA1138291 | organism-based format | Scientific Literature | |
6. | ALA901971 | Functional | Reduction of blood pressure in pig at 1 mg/kg, iv | Sus scrofa | 1 | ALA1138291 | organism-based format | Scientific Literature | |
7. | ALA901972 | Functional | Effect on rat portal vein | Rattus norvegicus | 1 | ALA1138291 | tissue-based format | Scientific Literature | |
8. | ALA901973 | ADME | Half life in dog at 100 nmol/kg, iv | Canis lupus familiaris | 2 | ALA1138291 | organism-based format | Scientific Literature | |
9. | ALA901975 | ADME | Plasma clearance in dog at 100 nmol/kg, iv | Canis lupus familiaris | 2 | ALA1138291 | organism-based format | Scientific Literature | |
10. | ALA901977 | ADME | Tmax in dog at 100 nmol/kg, po | Canis lupus familiaris | 2 | ALA1138291 | organism-based format | Scientific Literature | |
11. | ALA901979 | ADME | Half life in dog at 100 nmol/kg, po | Canis lupus familiaris | 2 | ALA1138291 | organism-based format | Scientific Literature | |
12. | ALA901981 | ADME | Oral bioavailability in dog at 100 nmol/kg, po | Canis lupus familiaris | 2 | ALA1138291 | organism-based format | Scientific Literature |