# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA902744 | B | Inhibition of human uPA | Homo sapiens | 20 | ALA1138351 | single protein format | Scientific Literature | |
2. | ALA902745 | B | Binding affinity to uPA | 16 | ALA1138351 | single protein format | Scientific Literature | ||
3. | ALA902746 | B | Inhibition of human recombinant tPA | Homo sapiens | 19 | ALA1138351 | single protein format | Scientific Literature | |
4. | ALA902747 | B | Selectivity index, ratio of IC50 for human recombinant tPA to IC50 for human uPA | Homo sapiens | 16 | ALA1138351 | assay format | Scientific Literature | |
5. | ALA902749 | B | Inhibition of human plasmin | Homo sapiens | 19 | ALA1138351 | single protein format | Scientific Literature | |
6. | ALA902751 | B | Inhibition of human thrombin | Homo sapiens | 16 | ALA1138351 | single protein format | Scientific Literature | |
7. | ALA902754 | B | Inhibition of factor 10a at 250 uM | 7 | ALA1138351 | single protein format | Scientific Literature | ||
8. | ALA902742 | B | Selectivity index, ratio of IC50 for human plasmin to IC50 for human uPA | Homo sapiens | 15 | ALA1138351 | assay format | Scientific Literature | |
9. | ALA902794 | B | Selectivity index, ratio of IC50 for human thrombin to IC50 for human uPA | Homo sapiens | 13 | ALA1138351 | assay format | Scientific Literature | |
10. | ALA3772516 | B | Inhibition of human recombinant KLK4 expressed in Escherichia coli using Bachem I-1120 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
11. | ALA3772517 | B | Inhibition of human recombinant KLK2 expressed in Escherichia coli using Bachem I-1295 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
12. | ALA3772518 | B | Inhibition of human recombinant KLK1 expressed in Escherichia coli using Bachem I-1295 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
13. | ALA3772679 | B | Inhibition of human recombinant KLK8 expressed in Escherichia coli using Bachem I-1120 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
14. | ALA3772680 | B | Inhibition of recombinant uPA (unknown origin) using Biophen CS-61(44) as substrate | Homo sapiens | 11 | ALA3769401 | single protein format | Scientific Literature | |
15. | ALA3772681 | B | Inhibition of recombinant tPA (unknown origin) using Biophen CS-05(88) as substrate | Homo sapiens | 11 | ALA3769401 | single protein format | Scientific Literature | |
16. | ALA3772682 | B | Inhibition of human plasma thrombin using Biophen CS-21(66) as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | cell-free format | Scientific Literature | |
17. | ALA3772683 | B | Inhibition of human plasma plasmin using Biophen CS-21(66) as substrate | Homo sapiens | 10 | ALA3769401 | cell-free format | Scientific Literature | |
18. | ALA3772684 | B | Inhibition of factor 10a (unknown origin) using Biophen CS-11(32) as substrate | Homo sapiens | 11 | ALA3769401 | single protein format | Scientific Literature | |
19. | ALA3772685 | B | Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by 5-5'-Dithiobis(2 nitrobenzoic acid)-based assay | Electrophorus electricus | 10 | ALA3769401 | single protein format | Scientific Literature | |
20. | ALA3772693 | B | Irreversible inhibition of recombinant uPA (unknown origin) using Biophen CS-61(44) as substrate at 100 times IC50 preincubated for 15 mins followed by 100 fold dilution measured for 1 hr | Homo sapiens | 4 | ALA3769401 | single protein format | Scientific Literature |