# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA898977 | B | Inhibition of integrin alpha-V-beta-3-mediated SK-MEL-24 cell adhesion to fibronectin | Homo sapiens | 16 | ALA1137514 | protein complex format | Scientific Literature | |
2. | ALA898978 | B | Inhibition of integrin alpha-5-beta-1-mediated K562 cell adhesion to fibronectin | Homo sapiens | 16 | ALA1137514 | cell-based format | Scientific Literature | |
3. | ALA3293387 | B | Antagonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as inhibition of fibronectin-mediated cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 1 | ALA3286198 | cell-based format | Scientific Literature | |
4. | ALA4681197 | T | Toxicity in human SK-MEL-24 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | ALA4680084 | cell-based format | Scientific Literature | |
5. | ALA4681198 | T | Toxicity in human MCF7 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | ALA4680084 | cell-based format | Scientific Literature | |
6. | ALA4681199 | T | Toxicity in human HT-29 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | ALA4680084 | cell-based format | Scientific Literature | |
7. | ALA4681200 | T | Toxicity in human K562 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | ALA4680084 | cell-based format | Scientific Literature | |
8. | ALA4681201 | T | Toxicity in human HEL cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | ALA4680084 | cell-based format | Scientific Literature | |
9. | ALA4681203 | B | Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 15 | ALA4680084 | cell-based format | Scientific Literature | |
10. | ALA4681207 | B | Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 15 | ALA4680084 | cell-based format | Scientific Literature | |
11. | ALA4681208 | B | Agonist activity at alphaVbeta6 in human HT-29 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 17 | ALA4680084 | cell-based format | Scientific Literature | |
12. | ALA4681209 | B | Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 18 | ALA4680084 | cell-based format | Scientific Literature | |
13. | ALA4681210 | B | Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 14 | ALA4680084 | cell-based format | Scientific Literature | |
14. | ALA4681211 | B | Antagonist activity at alpha5beta1 in human K562 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 11 | ALA4680084 | cell-based format | Scientific Literature | |
15. | ALA4681212 | B | Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and further incubated for 30 mins by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 14 | ALA4680084 | cell-based format | Scientific Literature | |
16. | ALA4681213 | B | Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 18 | ALA4680084 | cell-based format | Scientific Literature | |
17. | ALA4681214 | B | Antagonist activity at alpha2bbeta3 in human HEL cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 18 | ALA4680084 | cell-based format | Scientific Literature | |
18. | ALA4681215 | B | Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and further incubated for 30 mins by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 18 | ALA4680084 | cell-based format | Scientific Literature | |
19. | ALA4681216 | B | Agonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as increase in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 and further incubated for 30 mins by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 15 | ALA4680084 | cell-based format | Scientific Literature | |
20. | ALA4681217 | B | Antagonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 and further incubated for 30 mins by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 19 | ALA4680084 | cell-based format | Scientific Literature |