# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA902744 | B | Inhibition of human uPA | Homo sapiens | 20 | ALA1138351 | single protein format | Scientific Literature | |
2. | ALA902745 | B | Binding affinity to uPA | 16 | ALA1138351 | single protein format | Scientific Literature | ||
3. | ALA902746 | B | Inhibition of human recombinant tPA | Homo sapiens | 19 | ALA1138351 | single protein format | Scientific Literature | |
4. | ALA902747 | B | Selectivity index, ratio of IC50 for human recombinant tPA to IC50 for human uPA | Homo sapiens | 16 | ALA1138351 | assay format | Scientific Literature | |
5. | ALA902749 | B | Inhibition of human plasmin | Homo sapiens | 19 | ALA1138351 | single protein format | Scientific Literature | |
6. | ALA902751 | B | Inhibition of human thrombin | Homo sapiens | 16 | ALA1138351 | single protein format | Scientific Literature | |
7. | ALA902753 | B | Inhibition of factor 10a | 11 | ALA1138351 | single protein format | Scientific Literature | ||
8. | ALA902756 | P | Distribution coefficient, log D in octanol and phosphate buffer saline at pH 7.4 | 2 | ALA1138351 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA902757 | A | Apparent solubility in phosphate buffered saline at pH 7.4 after 2 hrs | 2 | ALA1138351 | assay format | Scientific Literature | ||
10. | ALA902758 | P | Chemical stability assessed as half life of hydrolysis at pH 1 | 2 | ALA1138351 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA902759 | P | Chemical stability assessed as half life of hydrolysis at pH 4 | 2 | ALA1138351 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA902760 | P | Chemical stability assessed as half life of hydrolysis at pH 7.4 | 2 | ALA1138351 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA902761 | P | Chemical stability assessed as half life of hydrolysis at pH 8.8 | 2 | ALA1138351 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA901748 | A | Stability in human plasma after 3 hrs | Homo sapiens | 2 | ALA1138351 | cell-free format | Scientific Literature | |
15. | ALA901749 | B | Inhibition of rat uPA | Rattus norvegicus | 2 | ALA1138351 | single protein format | Scientific Literature | |
16. | ALA901750 | B | Inhibition of mouse uPA | Mus musculus | 2 | ALA1138351 | single protein format | Scientific Literature | |
17. | ALA901751 | B | Inhibition of mouse plasmin | Mus musculus | 2 | ALA1138351 | single protein format | Scientific Literature | |
18. | ALA901752 | B | Inhibition of rat plasmin | Rattus norvegicus | 2 | ALA1138351 | single protein format | Scientific Literature | |
19. | ALA901753 | B | Inhibition of rat thrombin | Rattus norvegicus | 2 | ALA1138351 | single protein format | Scientific Literature | |
20. | ALA901754 | B | Inhibition of mouse thrombin | Mus musculus | 2 | ALA1138351 | single protein format | Scientific Literature |