# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA900188 | F | Inhibition of transthyretin fibril formation at pH 4.4 at 100 uM | 97 | ALA1138243 | assay format | Scientific Literature | ||
2. | ALA900190 | F | Inhibition of transthyretin amyloidosis assessed as fibril formation pH 4.4 at 100 uM | 95 | ALA1138243 | assay format | Scientific Literature | ||
3. | ALA1068581 | B | Inhibition of snake venom NPP1 assessed as release of p-nitrophenol after 30 mins by microtitre plate spectrophotometry | Naja naja | 26 | ALA1152665 | assay format | Scientific Literature | |
4. | ALA1068582 | B | Noncompetitive inhibition of snake venom NPP1 by Dixon plot analysis | Naja naja | 26 | ALA1152665 | assay format | Scientific Literature | |
5. | ALA1068584 | B | Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry | Homo sapiens | 12 | ALA1152665 | single protein format | Scientific Literature | |
6. | ALA1068585 | B | Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysis | Homo sapiens | 12 | ALA1152665 | single protein format | Scientific Literature | |
7. | ALA1166155 | B | Inhibition of mashroom tyrosinase | Agaricus bisporus | 26 | ALA1165921 | single protein format | Scientific Literature | |
8. | ALA3876008 | B | Inhibition of Escherichia coli K12 thymidine phosphorylase expressed in Escherichia coli preincubated for 10 mins followed by substrate addition measured up to 30 mins by spectrophotometric method | Escherichia coli K-12 | 3 | ALA3875181 | assay format | Scientific Literature | |
9. | ALA4124406 | B | Inhibition of thymidine phosphorylase (unknown origin) | Homo sapiens | 2 | ALA4118233 | single protein format | Scientific Literature | |
10. | ALA4733156 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv incubated for 7 days by microplate alamar blue assay | Mycobacterium tuberculosis | 2 | ALA4732049 | organism-based format | Scientific Literature | |
11. | ALA4733157 | A | Cytotoxicity against CHO-K1 cells incubated for 24 hrs by MTT assay | Cricetulus griseus | 1 | ALA4732049 | cell-based format | Scientific Literature | |
12. | ALA4733158 | T | Selectivity index, ratio of IC50 for CHO-K1 cells to MIC for Mycobacterium tuberculosis H37Rv | 1 | ALA4732049 | assay format | Scientific Literature | ||
13. | ALA5246869 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | Mycobacterium tuberculosis | 93 | ALA5244273 | organism-based format | Scientific Literature | |
14. | ALA5246875 | T | Cytotoxicity against Chinese hamster CHO-K1 cells assessed as inhibition of cell growth | Cricetulus griseus | 7 | ALA5244273 | cell-based format | Scientific Literature | |
15. | ALA5246876 | T | Selectivity index, ratio of IC50 for cytotoxicity against Chinese hamster CHO-K1 cells to MIC for antimycobacterial activity against Mycobacterium tuberculosis H37Rv | 7 | ALA5244273 | cell-based format | Scientific Literature | ||
16. | ALA5246877 | F | Antimycobacterial activity against isoniazid, streptomycin, ethambutol and ethionamide resistant Mycobacterium tuberculosis clinical isolate A | Mycobacterium tuberculosis | 3 | ALA5244273 | organism-based format | Scientific Literature | |
17. | ALA5246878 | F | Antimycobacterial activity against isoniazid and ethionamide resistant Mycobacterium tuberculosis clinical isolate B | Mycobacterium tuberculosis | 3 | ALA5244273 | organism-based format | Scientific Literature | |
18. | ALA5246879 | F | Antimycobacterial activity against isoniazid, streptomycin, and rifampicin resistant Mycobacterium tuberculosis clinical isolate C | Mycobacterium tuberculosis | 2 | ALA5244273 | organism-based format | Scientific Literature | |
19. | ALA5246880 | F | Antimycobacterial activity against isoniazid and rifampicin resistant Mycobacterium tuberculosis clinical isolate D | Mycobacterium tuberculosis | 1 | ALA5244273 | organism-based format | Scientific Literature | |
20. | ALA5246881 | F | Antimycobacterial activity against isoniazid and ethionamide resistant Mycobacterium tuberculosis clinical isolate E | Mycobacterium tuberculosis | 3 | ALA5244273 | organism-based format | Scientific Literature |