# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA681260 | B | Acceptor substrate specificity toward Fucosyltransferase for the galactosides of GlcNAc with beta 1,3 or beta 1,4-linkages | 19 | single protein format | Scientific Literature | |||
2. | ALA1614530 | F | PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] | Escherichia coli | 61,607 | assay format | PubChem BioAssays | ||
3. | ALA1614211 | F | PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) | 36,499 | assay format | PubChem BioAssays | |||
4. | ALA2354311 | F | PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) | 31,581 | cell-based format | PubChem BioAssays | |||
5. | ALA4419300 | B | Binding affinity to V5-His tagged FIBCD1 ecto-domain (54 to 461 residues) (unknown origin) expressed in HEK293 cells assessed as reduction in binding between FIBCD1 and acetylated BSA by ELISA | Homo sapiens | 16 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4419301 | B | Binding affinity to V5-His tagged FIBCD1 ecto-domain (54 to 461 residues) (unknown origin) assessed as reduction in binding between FIBCD1 and acetylated BSA by ELISA relative to control | Homo sapiens | 7 | single protein format | Patent Bioactivity Data | ||
7. | ALA4714715 | B | Modulation of human amyloid beta (1 to 42) supramolecular assembly assessed as elongation of amyloid beta42 fibrils at <50 mM measured for 10 days by ThT dye based fluorescence spectrophotometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
8. | ALA4714716 | B | Modulation of human amyloid beta (1 to 42) supramolecular assembly assessed as elongation of amyloidbeta42 fibrils at 50 mM measured for 10 days by ThT dye based fluorescence spectrophotometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
9. | ALA4714718 | B | Modulation of human amyloid beta (1 to 42) supramolecular organization assessed as reduction in antiparallel beta-sheets characteristic of cytotoxic Abeta42 aggregates at 1 mM measured for 5 days by CD spectrometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
10. | ALA4714719 | A | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 1 mM measured after 1 day by alamar blue assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA4714720 | F | Neuroprotective activity against Abeta-42-induced cytotoxicity in human SH-SY5Y cells assessed as increase in cell viability at 1 mM measured upto 5 days by alamar blue assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
12. | ALA4714724 | B | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as reduction in insulin resistance by measuring reduction in Abeta-42-induced IRS1 phosphorylation at Ser612 residue at 1 mM incubated for 1 hr by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA4714730 | B | Modulation of human amyloid beta (1 to 42) supramolecular organization at 0.4 mM by dynamic light scattering based analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
14. | ALA4714731 | B | Modulation of human amyloid beta (1 to 42) supramolecular organization assessed as prevalence of Abeta42 fibrils with parallel beta-sheets at 16 mM incubated for 5 days by ATR-FITR analysis | Homo sapiens | 4 | single protein format | Scientific Literature |