# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA624498 | A | Half-recovery time (T1/2) of the vascular resistance decrease at ED30 in anesthetized dogs | Canis lupus familiaris | 4 | ALA1124360 | organism-based format | Scientific Literature | |
2. | ALA876500 | A | Time to peak response on lowering of vascular resistance, in dogs when administered intravenously | Canis lupus familiaris | 4 | ALA1124360 | organism-based format | Scientific Literature | |
3. | ALA624608 | A | Hill coefficient of the compound | Rattus norvegicus | 8 | ALA1123385 | organism-based format | Scientific Literature | |
4. | ALA628290 | P | Calculated membrane partition coefficient (Kmemb) | 75 | ALA1149124 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA630098 | P | Partition coefficient (logP) | 28 | ALA1136781 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA631588 | F | Compound was tested for the plasma clearance in dogs | Canis lupus familiaris | 1 | ALA1123472 | organism-based format | Scientific Literature | |
7. | ALA633843 | F | Compound was tested for the plasma half life in dogs | 1 | ALA1123472 | cell-free format | Scientific Literature | ||
8. | ALA634455 | A | In vitro clearance in dog in 1000000 cells | Canis lupus familiaris | 17 | ALA1132496 | organism-based format | Scientific Literature | |
9. | ALA634457 | A | In vitro clearance in human in 1000000 cells | Homo sapiens | 19 | ALA1132496 | organism-based format | Scientific Literature | |
10. | ALA634458 | A | In vitro clearance in rat in 1000000 cells | Rattus norvegicus | 19 | ALA1132496 | organism-based format | Scientific Literature | |
11. | ALA634459 | A | In vivo clearance in dog | Canis lupus familiaris | 11 | ALA1132496 | organism-based format | Scientific Literature | |
12. | ALA875174 | A | In vivo clearance in human | Homo sapiens | 11 | ALA1132496 | organism-based format | Scientific Literature | |
13. | ALA635504 | A | In vivo clearance in rat | Rattus norvegicus | 11 | ALA1132496 | organism-based format | Scientific Literature | |
14. | ALA633649 | A | Delta logD (logD6.5 - logD7.4) | 111 | ALA1133765 | assay format | Scientific Literature | ||
15. | ALA634381 | F | Compound was tested for the volume of distribution in dogs | 1 | ALA1123472 | organism-based format | Scientific Literature | ||
16. | ALA634283 | P | Partition coefficient (logD6.5) | 114 | ALA1133765 | small-molecule physicochemical format | Scientific Literature | ||
17. | ALA641858 | A | Mean maximal plasma concentration | 1 | ALA1145124 | organism-based format | Scientific Literature | ||
18. | ALA645153 | P | Ionization constant (pKa) | 204 | ALA1133765 | small-molecule physicochemical format | Scientific Literature | ||
19. | ALA633098 | A | Oral bioavailability in human | Homo sapiens | 184 | ALA1133765 | organism-based format | Scientific Literature | |
20. | ALA649101 | B | Displacement of [3H](R)-PIA binding to Adenosine A1 receptor in rat brain membranes | 28 | ALA1129250 | cell membrane format | Scientific Literature |