# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA903344 | F | Growth inhibition of mouse L929 cells by MTT assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
2. | ALA1788041 | B | Inhibition of Manduca sexta V-ATPase V1/Vo holoenzyme activity assessed as inorganic phosphate production pretreated for 5 mins | Manduca sexta | 6 | single protein format | Scientific Literature | ||
3. | ALA1788042 | F | Antiproliferative activity against mouse L929 cells assessed as growth inhibition after 5 days by MTT assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
4. | ALA4381886 | A | Intrinsic clearance in CD1 mouse liver microsomes at 1 uM | Mus musculus | 2 | microsome format | Scientific Literature | ||
5. | ALA4381887 | A | Intrinsic clearance in Sprague-Dawley rat liver microsomes at 1 uM | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
6. | ALA4381889 | F | Growth inhibition of human 1321N1 cells incubated for 72 hrs by MTT assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
7. | ALA4381891 | B | Inhibition of human P2X3 assessed as reduction in agonist-induced intracellular Ca2+ concentration pre-incubated for 30 mins before agonist addition by calcium 5 dye based fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
8. | ALA4381892 | B | Displacement of [3H]PSB-11 from human A3 adenosine receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation counting method | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
9. | ALA4381893 | B | Inhibition of human leukocyte elastase assessed as reduction in pNA release using chromogenic MeO-Suc-Ala-Ala-Pro-Val-pNA substrate measured over 10 mins by spectrophotometry | Homo sapiens | 9 | single protein format | Scientific Literature | ||
10. | ALA4381894 | U | Ratio of IC50 for inhibition of Manduca sexta V-type proton ATPase assessed as reduction in inorganic phosphate production pre-inucubated for 5 mins before Tris-ATP addition and measured after 2 mins to IC50 for inhibition of human 1321N1 cells incubated for 72 hrs by MTT assay | 3 | assay format | Scientific Literature | |||
11. | ALA4381913 | B | Inhibition of human P2X3 expressed in human 1321N1 cell membranes assessed as reduction in ATP-induced inhibition of [35S]ATPgammaS binding at 1 pm to 10 mM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4381914 | B | Inhibition of trypsin (unknown origin) assessed as reduction in pNA release using chromogenic Suc-Ala-Ala-Pro-Arg-pNA substrate measured over 10 mins by spectrophotometry | Homo sapiens | 3 | protein format | Scientific Literature | ||
13. | ALA4381915 | B | Inhibition of cathepsin B (unknown origin) assessed as reduction in pNA release using chromogenic Z-Arg-Arg-pNA substrate measured over 1 hr by spectrophotometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
14. | ALA4381916 | B | Inhibition of cathepsin L (unknown origin) assessed as reduction in pNA release using chromogenic Z-Phe-Arg-pNA substrate measured over 1 hr by spectrophotometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
15. | ALA4381917 | B | Inhibition of chymotrypsin (unknown origin) assessed as reduction in pNA release using chromogenic Suc-Ala-Ala-Pro-Phe-pNA substrate measured over 12.5 mins by spectrophotometry | Homo sapiens | 3 | protein format | Scientific Literature | ||
16. | ALA4381918 | A | Intrinsic clearance in human liver microsomes at 1 uM | Homo sapiens | 1 | microsome format | Scientific Literature | ||
17. | ALA4381919 | A | Half life in CD1 mouse liver microsomes at 1 uM | Mus musculus | 1 | microsome format | Scientific Literature | ||
18. | ALA4381920 | A | Half life in Sprague-Dawley rat liver microsomes at 1 uM | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
19. | ALA4381921 | A | Half life in human liver microsomes at 1 uM | Homo sapiens | 1 | microsome format | Scientific Literature | ||
20. | ALA4381922 | A | Stability in CD1 mouse liver microsomes assessed as drug degradation at 1 uM measured within 15 mins | Mus musculus | 1 | microsome format | Scientific Literature |