# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615939 | Binding | In vitro displacement of [3H]8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor | 21 | ALA1129625 | tissue-based format | Scientific Literature | ||
2. | ALA643671 | Binding | Dopamine sensitive adenylate cyclase activity (stimulation) in homogenates of rat brain striatal tissue was assessed at 50 uM; + = <40% increase of cAMP above basal activity | 8 | ALA1121759 | tissue-based format | Scientific Literature | ||
3. | ALA884268 | Binding | Inhibition of [3H]apomorphine binding to calf caudate membrane preparation (p4) | 17 | ALA1121759 | assay format | Scientific Literature | ||
4. | ALA654452 | Binding | Inhibition of [3H]spiroperidol binding to calf caudate membrane preparation (p4) | 17 | ALA1121759 | assay format | Scientific Literature | ||
5. | ALA672009 | Binding | Binding affinity against Dopamine receptor D1 from rat brain corpus striatal preparations using [3H]SCH-23390 | 4 | ALA1124155 | assay format | Scientific Literature | ||
6. | ALA670279 | Binding | Compound was evaluated for its ability to inhibit Dopamine receptor D1 in rat striatum using [3H]SCH-23390 | 3 | ALA1125726 | tissue-based format | Scientific Literature | ||
7. | ALA670435 | Binding | In vitro displacement of [3H]SCH-23390 binding to rat striatal Dopamine receptor D1 | 17 | ALA1129625 | single protein format | Scientific Literature | ||
8. | ALA675706 | Binding | Binding affinity against dopamine agonist sites from rat brain corpus striatal preparations using [3H]ADTN | 4 | ALA1124155 | assay format | Scientific Literature | ||
9. | ALA675707 | Functional | Compound was evaluated for its ability to inhibit Striatal Dopamine receptor in rat brain through radioreceptor assay carried out with agonist ligand. | 3 | ALA1125726 | tissue-based format | Scientific Literature | ||
10. | ALA670880 | Binding | Displacement of [3H]raclopride from human Dopamine receptor D2A | Homo sapiens | 12 | ALA1129625 | single protein format | Scientific Literature | |
11. | ALA674980 | Binding | Binding affinity against Dopamine receptor D2 from rat brain corpus striatal preparations using [3H]spiperone | 4 | ALA1124155 | assay format | Scientific Literature | ||
12. | ALA674827 | Binding | Compound was evaluated for its ability to inhibit Dopamine receptor D2 in rat striatum using [3H]spiperone | 3 | ALA1125726 | tissue-based format | Scientific Literature | ||
13. | ALA846226 | Binding | Potency ratio calculated from the ratio of D2 to that of D1 receptors | 8 | ALA1125726 | protein format | Scientific Literature | ||
14. | ALA852491 | Binding | Potency of compound against D1 receptor to D2 receptor was determined | 4 | ALA1124155 | protein format | Scientific Literature | ||
15. | ALA944156 | Functional | Inhibition of rat midbrain dopaminergic neuron firing | Rattus norvegicus | 5 | ALA1141452 | tissue-based format | Scientific Literature | |
16. | ALA944157 | Binding | Inhibition of tyrosine hydroxylase | 4 | ALA1141452 | single protein format | Scientific Literature | ||
17. | ALA944160 | Binding | Displacement of [3H]SCH-23390 from rat dopamine D1 receptor | Rattus norvegicus | 69 | ALA1141452 | single protein format | Scientific Literature | |
18. | ALA944161 | Binding | Displacement of [3H]raclopride from rat dopamine D2 receptor | Rattus norvegicus | 89 | ALA1141452 | single protein format | Scientific Literature | |
19. | ALA944163 | Binding | Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor | Rattus norvegicus | 25 | ALA1141452 | single protein format | Scientific Literature | |
20. | ALA1065705 | Binding | Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation counting | 32 | ALA1159064 | cell-based format | Scientific Literature |