| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA923075 | B | Inhibition of human cathepsin S | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 2. | ALA923076 | B | Inhibition of human cathepsin K | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 3. | ALA923077 | B | Inhibition of human cathepsin B | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 4. | ALA923078 | B | Inhibition of human cathepsin L | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 5. | ALA923079 | B | Inhibition of mouse recombinant cathepsin S | Mus musculus | 10 | single protein format | Scientific Literature | ||
| 6. | ALA923080 | B | Inhibition of mouse recombinant cathepsin K | Mus musculus | 10 | single protein format | Scientific Literature | ||
| 7. | ALA923081 | B | Inhibition of mouse recombinant cathepsin B | Mus musculus | 10 | single protein format | Scientific Literature | ||
| 8. | ALA923082 | B | Inhibition of rat spleen cathepsin S | Rattus norvegicus | 10 | tissue-based format | Scientific Literature | ||
| 9. | ALA923083 | B | Inhibition of rat liver lysosomal cathepsin B | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
| 10. | ALA923084 | B | Inhibition of mouse recombinant cathepsin L | Mus musculus | 10 | single protein format | Scientific Literature | ||
| 11. | ALA923085 | B | Inhibition of rat liver lysosomal cathepsin L | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
| 12. | ALA923093 | A | AUC (0 to 24 hrs) in C57BL/6 mouse assessed as (R)-N-(1-cyanocyclopropyl)-3-(methylsulfonyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamide levels at 10 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA924117 | A | AUC (0 to 24 hrs) in C57BL/6 mouse assessed as (R)-N-(1-cyanocyclopropyl)-3-(methylsulfonyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamide levels at 50 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA924118 | A | AUC (0 to 24 hrs) in C57BL/6 mouse assessed as (R)-N-(1-cyanocyclopropyl)-3-(methylsulfonyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamide levels at 150 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA924119 | A | AUC (0 to 24 hrs) in C57BL/6 mouse assessed as (R)-N-(1-cyanocyclopropyl)-3-(methylsulfonyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamide levels at 0.01 w/w % after 5 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA924120 | A | AUC (0 to 24 hrs) in C57BL/6 mouse assessed as (R)-N-(1-cyanocyclopropyl)-3-(methylsulfonyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamide levels at 0.05 w/w % after 5 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA924121 | A | AUC (0 to 24 hrs) in C57BL/6 mouse assessed as (R)-N-(1-cyanocyclopropyl)-3-(methylsulfonyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamide levels at 0.25 w/w % after 5 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA924122 | A | Drug level in C57BL/6 mouse blood at 0.01 w/w % | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA924123 | A | Drug level in C57BL/6 mouse blood at 0.05 w/w % | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA924124 | A | Drug level in C57BL/6 mouse blood at 0.25 w/w % | Mus musculus | 1 | organism-based format | Scientific Literature |
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