# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA621158 | F | Irreversible inhibition of ATP binding site of EGFR (lack of phosphorylated EGFR) in A431 cells 8 hour after washing cells free of the inhibitor) | 17 | ALA1132213 | cell-based format | Scientific Literature | ||
2. | ALA674019 | B | Inhibition of EGF-stimulated autophosphorylation of EGFR enzyme in A431 cells detected by immunoblotting | 23 | ALA1133162 | cell-based format | Scientific Literature | ||
3. | ALA674020 | B | Inhibition of phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme prepared from human A431 carcinoma cell vesicles by immunoaffinity chromatography | 24 | ALA1133162 | single protein format | Scientific Literature | ||
4. | ALA674021 | F | Irreversible inhibition of formation of phosphorylated EGFR enzyme in A431 cells 8 hr after washing cells free of the inhibitor | 23 | ALA1133162 | cell-based format | Scientific Literature | ||
5. | ALA673949 | B | Inhibition of heregulin-stimulated autophosphorylation of ERBB2 receptor kinase in MDA-MB-453 cells. | Homo sapiens | 12 | ALA1132213 | cell-based format | Scientific Literature | |
6. | ALA673951 | B | Inhibition of autophosphorylation of ERBB2 receptor kinase in MDA-MB 453 cells | 14 | ALA1133162 | cell-based format | Scientific Literature | ||
7. | ALA679551 | B | Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor in A431 cells | Homo sapiens | 6 | ALA1132213 | cell-based format | Scientific Literature | |
8. | ALA856168 | B | Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR) | 6 | ALA1132213 | single protein format | Scientific Literature | ||
9. | ALA726618 | F | In vivo activity against A431 xenograft in nude mice, net reduction in tumor burden at 75 mg/kg ip dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
10. | ALA726269 | F | In vivo activity against H125 xenograft in nude mice, net reduction in tumor burden at 200 mg/kg dose | 3 | ALA1132213 | organism-based format | Scientific Literature | ||
11. | ALA726272 | F | In vivo activity against H125 xenograft in nude mice, net reduction in tumor burden at 250 mg/kg peroral dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
12. | ALA726273 | F | In vivo activity against H125 xenograft in nude mice, net reduction in tumor burden at 50 mg/kg ip dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
13. | ALA724290 | F | In vivo activity against H125 xenograft in nude mice, ratio of treated/control median tumor mass at 260 mg/kg peroral dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
14. | ALA724291 | F | In vivo activity against H125 xenograft in nude mice, ratio of treated/control median tumor mass at 250 mg/kg peroral dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
15. | ALA724292 | F | In vivo activity against H125 xenograft in nude mice, ratio of treated/control median tumor mass at 50 mg/kg ip dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
16. | ALA723391 | F | Difference in days for treated (T) and control (C) A431 cell tumors to reach 750 mg at 75 mg/kg ip dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
17. | ALA723392 | F | Difference in days for treated (T) and control (C) tumors to reach 750 mg at 250 mg/kg peroral dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
18. | ALA727315 | F | Difference in days for treated (T) and control (C) A431 cell tumors to reach 750 mg at 260 mg/kg peroral dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
19. | ALA727892 | F | Difference in days for treated (T) and control (C) H125 cell tumors to reach 750 mg at 50 mg/kg ip dose | 1 | ALA1132213 | organism-based format | Scientific Literature | ||
20. | ALA730266 | F | In vivo activity against A431 cell tumor xenograft in nude mice at 75 ip mg/kg dose | 1 | ALA1132213 | organism-based format | Scientific Literature |