#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA941841	B	Inhibition of HMG-CoA reductase in rat liver microsomes	Rattus norvegicus	41		microsome format	Scientific Literature
2.	ALA941842	F	Inhibition of cholesterol synthesis in rat hepatocytes	Rattus norvegicus	41		cell-based format	Scientific Literature
3.	ALA941843	F	Inhibition of cholesterol synthesis in L6 myocytes	Rattus norvegicus	41		cell-based format	Scientific Literature
4.	ALA941844	F	Inhibition of cholesterol synthesis in hamster at 10 mg/kg, po after 2 to 4 hrs relative to control	Cricetinae	9		organism-based format	Scientific Literature
5.	ALA941846	F	Inhibition of cholesterol synthesis in hamster at 10 mg/kg, po after 4 to 6 hrs relative to control	Cricetinae	12		organism-based format	Scientific Literature
6.	ALA1787314	B	Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrate addition measured after 0.75 hrs by beta scintillation counting	Rattus norvegicus	22		microsome format	Scientific Literature
7.	ALA1787315	F	Inhibition of cholesterol synthesis in rat hepatocytes assessed as reduction of [14C]-cholesterol level using [14C]-acetic acid preincubated for 4 hrs before addition of [14C]-acetic acid by liquid scintillation counting	Rattus norvegicus	19		cell-based format	Scientific Literature
8.	ALA1787316	F	Inhibition of cholesterol synthesis in rat L6 cells assessed as reduction of [14C]-cholesterol level using [14C]-acetic acid preincubated for 3 hrs before addition of [14C]-acetic acid by scintillation counting	Rattus norvegicus	19		cell-based format	Scientific Literature
9.	ALA1787317	F	Selectivity ratio of IC50 for cholesterol synthesis in rat hepatocytes to IC50 for cholesterol synthesis in rat L6 cells	Rattus norvegicus	18		cell-based format	Scientific Literature
10.	ALA1787318	F	Inhibition of cholesterol synthesis in golden syrian hamster assessed as reduction of [14C]-cholesterol level at 10 mg/kg, po followed by 2 hrs after treated with 80 uCi, ip of [14C]-sodium acetate measured after 4 hrs by liquid scintillation counting relative to control	Mesocricetus auratus	11		organism-based format	Scientific Literature
11.	ALA1787320	P	Lipophilicity, log D of the compound at pH 7.4 by shake flask method		16		small-molecule physicochemical format	Scientific Literature
12.	ALA1787321	F	Hypolipidemic activity in chow fed Hartley guinea pig assessed as reduction of LDL level administered orally for 7 days measured on day 8 after 2 hrs post dose	Cavia porcellus	4		organism-based format	Scientific Literature
13.	ALA1787322	A	Fraction unbound in rat plasma at 0.5 ug/ml	Rattus norvegicus	3		cell-free format	Scientific Literature
14.	ALA1787323	A	Fraction unbound in rat liver at 1 uM	Rattus norvegicus	3		tissue-based format	Scientific Literature
15.	ALA1787324	A	Fraction unbound in dog plasma at 0.5 ug/ml	Canis lupus familiaris	3		cell-free format	Scientific Literature
16.	ALA1787325	A	Fraction unbound in human plasma at 0.5 ug/ml	Homo sapiens	3		cell-free format	Scientific Literature
17.	ALA1787326	A	fAUC (0 to 24 hrs) in rat at 1 mg/kg, iv	Rattus norvegicus	2		organism-based format	Scientific Literature
18.	ALA1787327	A	fAUC (0 to 24 hrs) in rat at 10 mg/kg, po	Rattus norvegicus	2		organism-based format	Scientific Literature
19.	ALA1787328	A	fAUC (0 to 24 hrs) in dog at 1 mg/kg, iv	Canis lupus familiaris	2		organism-based format	Scientific Literature
20.	ALA1787329	A	fAUC (0 to 24 hrs) in dog at 5 mg/kg, po	Canis lupus familiaris	2		organism-based format	Scientific Literature