# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA662433 | B | In vitro inhibition of human placental Cytochrome P450 19A1 | Homo sapiens | 8 | ALA1126687 | assay format | Scientific Literature | |
2. | ALA851527 | B | Relative potency fr human placental cytochrome P450 compared to aminoglutethimide | Homo sapiens | 7 | ALA1126687 | assay format | Scientific Literature | |
3. | ALA915480 | B | Inhibition of human placental microsome CYP19 | Homo sapiens | 71 | ALA1139479 | assay format | Scientific Literature | |
4. | ALA1072072 | B | Inhibition of human CYP11B2 expressed in chinese hamster V79 cells | Homo sapiens | 47 | ALA1156929 | cell-based format | Scientific Literature | |
5. | ALA1072073 | B | Inhibition of human CYP11B1 expressed in chinese hamster V79 cells | Homo sapiens | 47 | ALA1156929 | cell-based format | Scientific Literature | |
6. | ALA1072074 | B | Selectivity ratio of IC50 for human CYP11B2 to IC50 human CYP11B1 | Homo sapiens | 43 | ALA1156929 | assay format | Scientific Literature | |
7. | ALA1211863 | B | Inhibition of human recombinant CYP11B2 by cell-based assay | Homo sapiens | 20 | ALA1208751 | cell-based format | Scientific Literature | |
8. | ALA1211864 | B | Inhibition of human recombinant CYP11B1 by cell-based assay | Homo sapiens | 20 | ALA1208751 | cell-based format | Scientific Literature | |
9. | ALA3101038 | B | Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assay | Rattus norvegicus | 4 | ALA3098017 | cell-based format | Scientific Literature | |
10. | ALA3101039 | B | Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assay | Rattus norvegicus | 4 | ALA3098017 | cell-based format | Scientific Literature | |
11. | ALA3101040 | B | Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assay | Homo sapiens | 6 | ALA3098017 | cell-based format | Scientific Literature | |
12. | ALA3101041 | B | Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assay | Homo sapiens | 6 | ALA3098017 | cell-based format | Scientific Literature | |
13. | ALA3101167 | B | Inhibition of human CYP19 preincubated for 10 mins followed by protein addition measured after 90 mins by fluorimetric analysis | Homo sapiens | 4 | ALA3098017 | single protein format | Scientific Literature | |
14. | ALA3101168 | B | Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIA | Homo sapiens | 25 | ALA3098017 | cell-based format | Scientific Literature | |
15. | ALA3366442 | B | Inhibition of human aldosterone synthase expressed in V79 MZ cells pretreated with compound for 1 hr followed by addition of 500 nM 11-deoxycorticosterone for 1hr by HPLC analysis | Homo sapiens | 4 | ALA3352462 | cell-based format | Scientific Literature | |
16. | ALA3366443 | B | Inhibition of human CYP11B1 expressed in V79 MZ cells pretreated with compound for 1 hr followed by addition of 500 nM 11-deoxycorticosterone for 3 hrs by HPLC analysis | Homo sapiens | 4 | ALA3352462 | cell-based format | Scientific Literature | |
17. | ALA3366444 | F | Decrease in myocardial fibrosis in SHR rat at 1.2 mg/kg/day, po | Rattus norvegicus | 1 | ALA3352462 | organism-based format | Scientific Literature | |
18. | ALA4012481 | B | Inhibition of human CYP11B2 expressed in HEK293A cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition measured after 1 hr by HTRF assay | Homo sapiens | 23 | ALA4011612 | cell-based format | Scientific Literature | |
19. | ALA4012482 | B | Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after 2 hrs by HTRF assay | Mus musculus | 22 | ALA4011612 | cell-based format | Scientific Literature | |
20. | ALA4012483 | A | Inhibition of human CYP11B1 expressed in HEK293A cells | Homo sapiens | 22 | ALA4011612 | cell-based format | Scientific Literature |