# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA926728 | B | Inhibition of Trypanosoma brucei cathepsin B-like cysteine protease | Trypanosoma brucei | 56 | single protein format | Scientific Literature | ||
2. | ALA926729 | F | Antitrypanosomal activity against Trypanosoma brucei | Trypanosoma brucei | 58 | organism-based format | Scientific Literature | ||
3. | ALA926730 | B | Inhibition of human liver cathepsin L | Homo sapiens | 56 | assay format | Scientific Literature | ||
4. | ALA926731 | B | Inhibition of human liver cathepsin B | Homo sapiens | 58 | assay format | Scientific Literature | ||
5. | ALA1109909 | F | Antitrypanosomal activity against Trypanosoma brucei brucei 427-221a after 40 hrs by bioluminescence assay | Trypanosoma brucei brucei | 24 | organism-based format | Scientific Literature | ||
6. | ALA1109910 | B | Inhibition of Trypanosoma brucei brucei recombinant rhodesain after 5 mins by spectrofluorimetry | Trypanosoma brucei brucei | 23 | assay format | Scientific Literature | ||
7. | ALA1109911 | B | Inhibition of Trypanosoma brucei brucei recombinant cathepsin B assessed after 5 mins by spectrofluorimetry | Trypanosoma brucei brucei | 23 | assay format | Scientific Literature | ||
8. | ALA1109913 | A | Cytotoxicity against HEK293 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA1109916 | T | Selectivity index, ratio of EC50 for HEK293 cells to EC50 for Trypanosoma brucei brucei | 2 | cell-based format | Scientific Literature | |||
10. | ALA1291578 | A | Cytotoxicity against human HEK293 cells after 72 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA1291579 | A | Cytotoxicity against human HepG2 cells after 72 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA1291580 | A | Cytotoxicity against human BJ cells after 72 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA1291581 | A | Cytotoxicity against human Raji cells after 72 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA1291582 | T | Toxicity in human erythrocyte assessed as hemolysis at 10 uM after 5 hrs | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
15. | ALA1291583 | P | Chemical stability in dimethyl sulfoxide at pH 3 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA1291584 | P | Chemical stability in dimethyl sulfoxide at pH 5 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA1291585 | P | Chemical stability in dimethyl sulfoxide at pH 7.4 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
18. | ALA1291586 | P | Chemical stability in phosphate buffered saline at pH 3 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
19. | ALA1291587 | P | Chemical stability in phosphate buffered saline at pH 5 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
20. | ALA1291588 | P | Chemical stability in phosphate buffered saline at pH 7.4 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature |