# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA926728 | B | Inhibition of Trypanosoma brucei cathepsin B-like cysteine protease | Trypanosoma brucei | 56 | single protein format | Scientific Literature | ||
2. | ALA926729 | F | Antitrypanosomal activity against Trypanosoma brucei | Trypanosoma brucei | 58 | organism-based format | Scientific Literature | ||
3. | ALA926730 | B | Inhibition of human liver cathepsin L | Homo sapiens | 56 | assay format | Scientific Literature | ||
4. | ALA926731 | B | Inhibition of human liver cathepsin B | Homo sapiens | 58 | assay format | Scientific Literature | ||
5. | ALA1291578 | A | Cytotoxicity against human HEK293 cells after 72 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA1291579 | A | Cytotoxicity against human HepG2 cells after 72 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA1291580 | A | Cytotoxicity against human BJ cells after 72 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA1291581 | A | Cytotoxicity against human Raji cells after 72 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA1291582 | T | Toxicity in human erythrocyte assessed as hemolysis at 10 uM after 5 hrs | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
10. | ALA1291583 | P | Chemical stability in dimethyl sulfoxide at pH 3 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA1291584 | P | Chemical stability in dimethyl sulfoxide at pH 5 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA1291585 | P | Chemical stability in dimethyl sulfoxide at pH 7.4 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
13. | ALA1291586 | P | Chemical stability in phosphate buffered saline at pH 3 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA1291587 | P | Chemical stability in phosphate buffered saline at pH 5 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA1291588 | P | Chemical stability in phosphate buffered saline at pH 7.4 after 14 days | 3 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA1291589 | A | Half life in CD1 mouse liver microsomes by UPLC-MS analysis | Mus musculus | 6 | microsome format | Scientific Literature | ||
17. | ALA1291590 | A | Half life in CD1 mouse plasma by UPLC-MS analysis | Mus musculus | 6 | cell-free format | Scientific Literature | ||
18. | ALA1291591 | A | Permeability of the compound assessed as ratio of compound in acceptor chamber to amount of compound in donor chamber at pH 3 by PAMPA assay | 3 | assay format | Scientific Literature | |||
19. | ALA1291592 | A | Permeability of the compound assessed as ratio of compound in acceptor chamber to amount of compound in donor chamber at pH 5 by PAMPA assay | 2 | assay format | Scientific Literature | |||
20. | ALA1291593 | A | Permeability of the compound assessed as ratio of compound in acceptor chamber to amount of compound in donor chamber at pH 7.4 by PAMPA assay | 3 | assay format | Scientific Literature |