# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA943064 | B | Displacement of fluorescent labelled VER-00051001 from human Hsp90-beta by FP assay | Homo sapiens | 55 | protein format | Scientific Literature | ||
2. | ALA943065 | F | Growth inhibition of human HCT116 cells after 24 hrs by SRB assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
3. | ALA943066 | A | Tmax in human HCT116 cells bearing NCr athymic mouse at 4 mg/kg, cassette dosing | Mus musculus | 5 | organism-based format | Scientific Literature | ||
4. | ALA943067 | A | Cmax in human HCT116 cells bearing NCr athymic mouse at 4 mg/kg, cassette dosing | Mus musculus | 5 | organism-based format | Scientific Literature | ||
5. | ALA943068 | A | AUClast in human HCT116 cells bearing NCr athymic mouse at 4 mg/kg, cassette dosing | Mus musculus | 5 | organism-based format | Scientific Literature | ||
6. | ALA943069 | A | Terminal half life in human HCT116 cells bearing NCr athymic mouse at 4 mg/kg, cassette dosing | Mus musculus | 5 | organism-based format | Scientific Literature | ||
7. | ALA943070 | A | Apparent pseudo steady-state volume of distribution in human HCT116 cells bearing NCr athymic mouse at 4 mg/kg, cassette dosing | Mus musculus | 5 | organism-based format | Scientific Literature | ||
8. | ALA943071 | A | Apparent clearance in in human HCT116 cells bearing NCr athymic mouse at 4 mg/kg, cassette dosing | Mus musculus | 5 | organism-based format | Scientific Literature | ||
9. | ALA943072 | F | Growth inhibition of human DU145 cells by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA943073 | F | Growth inhibition of human PC3M cells by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA943074 | F | Growth inhibition of human SKMel28 cells by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA943075 | F | Growth inhibition of human SF268 cells by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA943076 | F | Growth inhibition of human U87MG cells by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA943077 | F | Inhibition of tumor growth in human HCT116 cells bearing mouse assessed as tumor weight at 50 mg/kg, ip qd after 12 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
15. | ALA2114803 | F | PubChem BioAssay. Cell Proliferation Assay against the TMD8 Cell Line (Caspase readout at 8 hrs). (Class of assay: confirmatory) | 226 | assay format | PubChem BioAssays | |||
16. | ALA1020371 | F | Antiproliferative against human HCT116 cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
17. | ALA1023069 | F | Antitumor activity in human HCT116 cells xenografted mouse assessed as inhibition of tumor growth at 50 mg/kg, ip | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
18. | ALA1103007 | B | Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
19. | ALA1103009 | B | Inhibition of HSP90-mediated client protein HER2 degradation | 9 | single protein format | Scientific Literature | |||
20. | ALA1103010 | A | Half life in plasma of mouse bearing human WM266.4 cells at 50 mg/kg, iv | Mus musculus | 1 | organism-based format | Scientific Literature |