# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3538068 | ADME | Activity of human recombinant CYP2C19.1A mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
2. | ALA3538069 | ADME | Activity of human recombinant CYP2C19.1B mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
3. | ALA3538070 | ADME | Activity of human recombinant CYP2C19.5B mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
4. | ALA3538071 | ADME | Activity of human recombinant CYP2C19.6 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
5. | ALA3538072 | ADME | Activity of human recombinant CYP2C19.8 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
6. | ALA3538073 | ADME | Activity of human recombinant CYP2C19.9 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
7. | ALA3538074 | ADME | Activity of human recombinant CYP2C19.10 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
8. | ALA3538075 | ADME | Activity of human recombinant CYP2C19.11 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
9. | ALA3538076 | ADME | Activity of human recombinant CYP2C19.13 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
10. | ALA3538077 | ADME | Activity of human recombinant CYP2C19.14 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
11. | ALA3538078 | ADME | Activity of human recombinant CYP2C19.15 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
12. | ALA3538079 | ADME | Activity of human recombinant CYP2C19.16 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
13. | ALA3538080 | ADME | Activity of human recombinant CYP2C19.18 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
14. | ALA3538081 | ADME | Activity of human recombinant CYP2C19.19 mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
15. | ALA3538313 | ADME | Activity of human recombinant CYP2C19 E92D mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
16. | ALA3538314 | ADME | Activity of human recombinant CYP2C19 A161P mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
17. | ALA3538315 | ADME | Activity of human recombinant CYP2C19 D360N mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
18. | ALA3538316 | ADME | Activity of human recombinant CYP2C19 M74T mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
19. | ALA3538317 | ADME | Activity of human recombinant CYP2C19 F168L mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature | |
20. | ALA3538318 | ADME | Activity of human recombinant CYP2C19 E122A mutant expressed in Saccharomyces cerevisiae BJ5457 assessed as omeprazole 5'-hydroxylation per pmol protein at 5 uM after 60 mins | Homo sapiens | 1 | ALA3526057 | assay format | Scientific Literature |