# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA926257 | F | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D6 by LDH reporter assay | Plasmodium falciparum | 42 | organism-based format | Scientific Literature | ||
2. | ALA1055850 | F | Antitrypanosomal activity against Trypanosoma brucei rhodesiense STIB900 | Trypanosoma brucei rhodesiense | 40 | organism-based format | Scientific Literature | ||
3. | ALA1055851 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Trypanosoma brucei rhodesiense STIB900 | 40 | cell-based format | Scientific Literature | |||
4. | ALA1055852 | F | Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 | Plasmodium falciparum | 39 | organism-based format | Scientific Literature | ||
5. | ALA1055853 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for chloroquine-resistant Plasmodium falciparum K1 | 39 | cell-based format | Scientific Literature | |||
6. | ALA1055854 | F | Antileishmanial activity against Leishmania donovani MHOM/SD/62/1S-CL2D amastigotes | Leishmania donovani | 33 | organism-based format | Scientific Literature | ||
7. | ALA1055855 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Leishmania donovani MHOM/SD/62/1S-CL2D amastigotes | 32 | cell-based format | Scientific Literature | |||
8. | ALA1055856 | A | Cytotoxicity against rat L6 cells | Rattus norvegicus | 43 | cell-based format | Scientific Literature | ||
9. | ALA1056600 | F | Antitrypanosomal activity against Trypanosoma brucei rhodesiense STIB900 infected NMRI mouse assessed mean survival time at 10 mg/kg, ip dosed for 4 days | Trypanosoma brucei rhodesiense | 3 | organism-based format | Scientific Literature | ||
10. | ALA3057097 | U | Selectivity index, ratio of GI50 for human tumor cells to IC50 for Pneumocystis carini | 18 | assay format | Scientific Literature | |||
11. | ALA3057100 | A | Growth inhibition of Homo sapiens (human) ovarian cancer cells after 48 hr by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA3057103 | B | Binding affinity to Poly (dA-dT) DNA at 1:5 compound to DNA base pair ratio | 18 | assay format | Scientific Literature | |||
13. | ALA3057105 | A | Cytotoxicity against Homo sapiens (human) MCF7 cells at 100 uM after 48 hr by SRB assay relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
14. | ALA3057106 | A | Cytotoxicity against Homo sapiens (human) NCI-H460 cells at 100 uM after 48 hr by SRB assay relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
15. | ALA3056593 | A | Cytotoxicity against Homo sapiens (human) SF268 cells at 100 uM after 48 hr by SRB assay relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
16. | ALA3056594 | F | Antimicrobial activity against Pneumocystis carinii assessed as ATP level detection by bioluminescence assay | Pneumocystis carinii | 18 | organism-based format | Scientific Literature | ||
17. | ALA3056596 | B | Binding affinity to Bos taurus (calf) thymus DNA at 1:5 compound to DNA base pair ratio | Bos taurus | 18 | nucleic acid format | Scientific Literature | ||
18. | ALA3595950 | B | Displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor by beta counting analysis in absence of spermine | Rattus norvegicus | 81 | assay format | Scientific Literature | ||
19. | ALA3595951 | B | Displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor by beta counting analysis in presence of 30 uM spermine | Rattus norvegicus | 79 | assay format | Scientific Literature | ||
20. | ALA3595952 | B | Ratio of IC50 for displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor in presence of 30 uM spermine to IC50 for displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor in absence of 30 spermine | Rattus norvegicus | 79 | assay format | Scientific Literature |