| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3607621 | Binding | Inhibition of pre-miR-372 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | Not specified | 11 | ALA3603759 | assay format | Scientific Literature | |
| 2. | ALA3607622 | Binding | Inhibition of pre-miR-373 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | Not specified | 11 | ALA3603759 | assay format | Scientific Literature | |
| 3. | ALA3607623 | Binding | Inhibition of pre-miR-17 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | Not specified | 11 | ALA3603759 | assay format | Scientific Literature | |
| 4. | ALA3607624 | Binding | Inhibition of pre-miR-21 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | Not specified | 11 | ALA3603759 | assay format | Scientific Literature | |
| 5. | ALA3607625 | Binding | Inhibition of pre-miR-372 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | Not specified | 18 | ALA3603759 | assay format | Scientific Literature | |
| 6. | ALA3607729 | Binding | Inhibition of pre-miR-17 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | Not specified | 18 | ALA3603759 | assay format | Scientific Literature | |
| 7. | ALA3607730 | Binding | Inhibition of pre-miR-373 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | Not specified | 18 | ALA3603759 | assay format | Scientific Literature | |
| 8. | ALA3607731 | Binding | Inhibition of pre-miR-21 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | Not specified | 18 | ALA3603759 | assay format | Scientific Literature | |
| 9. | ALA3607732 | Binding | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay | Not specified | 18 | ALA3603759 | assay format | Scientific Literature | |
| 10. | ALA3607733 | Binding | Binding affinity to 5'-FAM-pre-miR-17 (unknown origin) after 4 hrs by fluorescence assay | Not specified | 18 | ALA3603759 | assay format | Scientific Literature | |
| 11. | ALA3607734 | Binding | Binding affinity to 5'-FAM-pre-miR-373 (unknown origin) after 4 hrs by fluorescence assay | Not specified | 18 | ALA3603759 | assay format | Scientific Literature | |
| 12. | ALA3607735 | Binding | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay in presence of 100-fold excess of Escherichia coli tRNA | Not specified | 11 | ALA3603759 | assay format | Scientific Literature | |
| 13. | ALA3607736 | Binding | Ratio of Kd for 5'-FAM-pre-miR-372 (unknown origin) in presence of 100-fold excess of Escherichia coli tRNA to Kd for 5'-FAM-pre-miR-372 (unknown origin) | Not specified | 11 | ALA3603759 | assay format | Scientific Literature | |
| 14. | ALA3607737 | Binding | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay in presence of 100-fold excess of 15-mer DNA | Not specified | 11 | ALA3603759 | assay format | Scientific Literature | |
| 15. | ALA3607738 | Binding | Ratio of Kd for 5'-FAM-pre-miR-372 (unknown origin) in presence of 100-fold excess of 15-mer DNA to Kd for 5'-FAM-pre-miR-372 (unknown origin) | Not specified | 11 | ALA3603759 | assay format | Scientific Literature | |
| 16. | ALA3607748 | Binding | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) assessed as change in total free energy by thermodynamic assay | Not specified | 9 | ALA3603759 | assay format | Scientific Literature | |
| 17. | ALA650218 | Functional | Beta-blocking activity measured by applying the stepwise linear discriminate analysis; Inactive | 48 | ALA1129855 | assay format | Scientific Literature | ||
| 18. | ALA926687 | ADME | Oral bioavailability in human | Homo sapiens | 295 | ALA1141299 | organism-based format | Scientific Literature | |
| 19. | ALA1217000 | Functional | Antimicrobial activity against Plasmodium falciparum | Plasmodium falciparum | 630 | ALA1212812 | organism-based format | Scientific Literature | |
| 20. | ALA1738606 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] | Homo sapiens | 13,828 | ALA1201862 | assay format | PubChem BioAssays |
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