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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA926687 A Oral bioavailability in human Homo sapiens 295 ALA1141299 organism-based format Scientific Literature 2. ALA3392937 F DNDI: Chagas in Vitro, 96 hour Trypanosoma cruzi 98 ALA3392926 organism-based format Drugs for Neglected Diseases Initiative (DNDi) 3. ALA3392938 F DNDI: Cytotoxicity in Vitro, 72 hour, in rat skeletal myoblast cells Rattus norvegicus 98 ALA3392926 cell-based format Drugs for Neglected Diseases Initiative (DNDi) 4. ALA3392939 F DNDI: Cytotoxicity in Vitro, 96 hour, in mouse macrophages (infected-amastigotes) Mus musculus 98 ALA3392926 cell-based format Drugs for Neglected Diseases Initiative (DNDi) 5. ALA3392940 F DNDI: Cytotoxicity in Vitro, 96 hour, in primary peritoneal mouse macrophages Mus musculus 11 ALA3392926 cell-based format Drugs for Neglected Diseases Initiative (DNDi) 6. ALA3392941 F DNDI: HAT in Vitro, 72 hour Trypanosoma brucei rhodesiense 98 ALA3392926 organism-based format Drugs for Neglected Diseases Initiative (DNDi) 7. ALA3392942 F DNDI: Leish (axenic) in Vitro, 72 hour Leishmania donovani 98 ALA3392926 organism-based format Drugs for Neglected Diseases Initiative (DNDi) 8. ALA3392943 F DNDI: Leish (macro) in Vitro, 96 hour Leishmania donovani 98 ALA3392926 organism-based format Drugs for Neglected Diseases Initiative (DNDi) 9. ALA4013915 B Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed by H2O2 addition measured after 5 mins Homo sapiens 33 ALA4011652 single protein format Scientific Literature 10. ALA4013917 B Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidation by measuring residual activity at 5 uM in absence of H2O2 incubated for 5 mins followed by 100 fold enzyme dilution relative to control Homo sapiens 9 ALA4011652 single protein format Scientific Literature 11. ALA4013918 B Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidation by measuring residual activity at 5 uM in presence of H2O2 incubated for 5 mins followed by 100 fold enzyme dilution relative to control Homo sapiens 9 ALA4011652 single protein format Scientific Literature 12. ALA4013919 B Inhibition of recombinant MPO (unknown origin) assessed as reduction in TMB peroxidation by measuring residual activity at 5 uM in presence of H2O2 and NaCl incubated for 5 mins followed by 100 fold enzyme dilution relative to control Homo sapiens 9 ALA4011652 single protein format Scientific Literature 13. ALA4013920 B Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISA Homo sapiens 9 ALA4011652 single protein format Scientific Literature 14. ALA4013924 B Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins Bos taurus 12 ALA4011652 single protein format Scientific Literature 15. ALA4013941 A Cytotoxicity against NHDF assessed as reduction in cell viability after 72 hrs by MTT assay Homo sapiens 8 ALA4011652 cell-based format Scientific Literature 16. ALA4013945 B Selectivity ratio of IC50 for bovine milk LPO to IC50 for recombinant MPO (unknown origin) 12 ALA4011652 assay format Scientific Literature 17. ALA4013947 A Substrate activity at CYP2D6 (unknown origin) Homo sapiens 2 ALA4011652 single protein format Scientific Literature 18. ALA4013948 A Substrate activity at CYP3A4 (unknown origin) Homo sapiens 1 ALA4011652 single protein format Scientific Literature