# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA945976 | F | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 | Plasmodium falciparum | 12 | organism-based format | Scientific Literature | ||
2. | ALA945977 | A | Cytotoxicity against HUVEC cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
3. | ALA945978 | F | Ratio of IC50 for human HUVEC cells to IC50 for Plasmodium falciparum W2 | 11 | cell-based format | Scientific Literature | |||
4. | ALA1681215 | F | Antiplasmodial activity against chloroquine-resistant ring stage Plasmodium falciparum W2 infected in human red blood cells after 48 hrs | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
5. | ALA1681216 | F | Antiplasmodial activity against chloroquine-sensitive ring stage Plasmodium falciparum 3D7 infected in human red blood cells after 48 hrs | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
6. | ALA1681217 | F | Antiplasmodial activity against chloroquine and pyrimethamine-resistant ring stage Plasmodium falciparum V1/S infected in human red blood cells after 48 hrs | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
7. | ALA1681218 | F | Antiplasmodial activity against chloroquine-sensitive, mefloquine-resistant ring stage Plasmodium falciparum D6 infected in human red blood cells after 48 hrs | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
8. | ALA1681219 | A | Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay | Chlorocebus sabaeus | 26 | cell-based format | Scientific Literature | ||
9. | ALA1681220 | T | Selectivity index, ratio of IC50 for african green monkey Vero cells to IC50 for chloroquine-resistant ring stage Plasmodium falciparum W2 | 26 | cell-based format | Scientific Literature | |||
10. | ALA1681221 | F | Resistance index, ratio of IC50 for chloroquine-resistant ring stage Plasmodium falciparum W2 to IC50 for chloroquine-sensitive ring stage Plasmodium falciparum 3D7 | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
11. | ALA1681228 | B | Binding affinity to heme by UV-visible titration | 26 | assay format | Scientific Literature | |||
12. | ALA1681229 | B | Binding affinity to s(GATCCTAGGATC)2-DNA by fluorescence spectroscopy | 25 | nucleic acid format | Scientific Literature | |||
13. | ALA1681230 | B | Inhibition of Plasmodium falciparum falcipain 2 | Plasmodium falciparum | 26 | assay format | Scientific Literature | ||
14. | ALA1681231 | B | Inhibition of Plasmodium falciparum falcipain 3 | Plasmodium falciparum | 26 | assay format | Scientific Literature | ||
15. | ALA1292260 | P | Dissociation constant, pKa of the compound by UV-visible spectroscopy | 21 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA1292262 | A | Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay | Chlorocebus sabaeus | 22 | cell-based format | Scientific Literature | ||
17. | ALA2090694 | F | Antitrypanosomal activity against Trypanosoma brucei brucei | Trypanosoma brucei brucei | 22 | organism-based format | Scientific Literature | ||
18. | ALA2090695 | B | Inhibition of Trypanosoma cruzi cruzaine | Trypanosoma cruzi | 22 | assay format | Scientific Literature | ||
19. | ALA2090696 | B | Inhibition of Trypanosoma brucei CatB | Trypanosoma brucei | 22 | single protein format | Scientific Literature | ||
20. | ALA2090697 | B | Inhibition of Trypanosoma brucei rhodesiense rhodesain | Trypanosoma brucei rhodesiense | 22 | single protein format | Scientific Literature |