# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2090694 | F | Antitrypanosomal activity against Trypanosoma brucei brucei | Trypanosoma brucei brucei | 22 | organism-based format | Scientific Literature | ||
2. | ALA2090695 | B | Inhibition of Trypanosoma cruzi cruzaine | Trypanosoma cruzi | 22 | assay format | Scientific Literature | ||
3. | ALA2090696 | B | Inhibition of Trypanosoma brucei CatB | Trypanosoma brucei | 22 | single protein format | Scientific Literature | ||
4. | ALA2090697 | B | Inhibition of Trypanosoma brucei rhodesiense rhodesain | Trypanosoma brucei rhodesiense | 22 | single protein format | Scientific Literature | ||
5. | ALA2090698 | A | Cytotoxicity against african green monkey Vero cells | Chlorocebus sabaeus | 22 | cell-based format | Scientific Literature | ||
6. | ALA2090699 | F | Selectivity index, ratio of CC50 for african green monkey Vero cells to IC50 for Trypanosoma brucei brucei | 22 | cell-based format | Scientific Literature | |||
7. | ALA945976 | F | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 | Plasmodium falciparum | 12 | organism-based format | Scientific Literature | ||
8. | ALA945977 | A | Cytotoxicity against HUVEC cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
9. | ALA945978 | F | Ratio of IC50 for human HUVEC cells to IC50 for Plasmodium falciparum W2 | 11 | cell-based format | Scientific Literature | |||
10. | ALA1681215 | F | Antiplasmodial activity against chloroquine-resistant ring stage Plasmodium falciparum W2 infected in human red blood cells after 48 hrs | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
11. | ALA1681216 | F | Antiplasmodial activity against chloroquine-sensitive ring stage Plasmodium falciparum 3D7 infected in human red blood cells after 48 hrs | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
12. | ALA1681217 | F | Antiplasmodial activity against chloroquine and pyrimethamine-resistant ring stage Plasmodium falciparum V1/S infected in human red blood cells after 48 hrs | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
13. | ALA1681218 | F | Antiplasmodial activity against chloroquine-sensitive, mefloquine-resistant ring stage Plasmodium falciparum D6 infected in human red blood cells after 48 hrs | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
14. | ALA1681219 | A | Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay | Chlorocebus sabaeus | 26 | cell-based format | Scientific Literature | ||
15. | ALA1681220 | T | Selectivity index, ratio of IC50 for african green monkey Vero cells to IC50 for chloroquine-resistant ring stage Plasmodium falciparum W2 | 26 | cell-based format | Scientific Literature | |||
16. | ALA1681221 | F | Resistance index, ratio of IC50 for chloroquine-resistant ring stage Plasmodium falciparum W2 to IC50 for chloroquine-sensitive ring stage Plasmodium falciparum 3D7 | Plasmodium falciparum | 27 | organism-based format | Scientific Literature | ||
17. | ALA1681222 | F | Antiplasmodial activity against GFP-expressing liver stage Plasmodium berghei sporozoites infected in human Huh-7 cells at 5 uM by fluorescence activated cell sorting based method | Plasmodium berghei | 2 | organism-based format | Scientific Literature | ||
18. | ALA1681223 | A | Drug uptake in Plasmodium falciparum infected in human erythrocyte nucleus at 5 uM after 3 hrs by fluorescence microscopy | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA1681224 | A | Drug uptake in Plasmodium falciparum infected in human erythrocyte food vacuoles at 5 uM after 3 hrs by fluorescence microscopy | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA1681225 | F | Inhibition of hematin assessed as quenching fluorescence intensity at 1:1 drug-hematin ratio by UV-visible titration | 1 | assay format | Scientific Literature |