# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA929054 | B | Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 13 | assay format | Scientific Literature | ||
2. | ALA3395080 | B | Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation | Homo sapiens | 27 | single protein format | Scientific Literature | ||
3. | ALA3395081 | B | Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation | Homo sapiens | 27 | single protein format | Scientific Literature | ||
4. | ALA3395082 | B | Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylation | Homo sapiens | 27 | single protein format | Scientific Literature | ||
5. | ALA3395083 | P | Solubility in buffer assessed as light scattering | 7 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA3395084 | B | Selectivity index, ratio of IC50 for PTP1B (unknown origin) to IC50 for PRL3 (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature | ||
7. | ALA3395085 | B | Selectivity index, ratio of IC50 for TCPTP (unknown origin) to IC50 for PRL3 (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature | ||
8. | ALA3395086 | A | Cytotoxicity against human HEK293 cells expressing human PRL-3 at 50 to 75 uM after 16 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
9. | ALA3395087 | B | Selectivity index, ratio of IC50 for VHR (unknown origin) to IC50 for PRL3 (unknown origin) | Homo sapiens | 7 | assay format | Scientific Literature | ||
10. | ALA3395090 | B | Inhibition of PRL-3-mediated cell migration in human HEK293 cells expressing PRL-3 (unknown origin) assessed as reduction of cell migrated at 75 uM for 16 hrs by transwell migration assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA4434548 | B | Inhibition of recombinant human PTP4A3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 5 mins in presence of DTT | Homo sapiens | 3 | assay format | Scientific Literature |