| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA635388 | P | Apparent partion coefficient of compound was evaluated in octanol/buffer at pH of 7.4 at 37 degree Centigrade | 11 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA635389 | P | Partition coefficient (logD7.4) | 21 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA640031 | F | Efficacy against alpha 1A adrenoceptor in human expressed as phenylephrine response at the dose of 40 uM | 26 | assay format | Scientific Literature | |||
| 4. | ALA640032 | F | Agonist potency against cloned human alpha 1A adrenoceptor expressed in rat-1 fibroblasts. | 29 | assay format | Scientific Literature | |||
| 5. | ALA858092 | F | Potency against cloned human alpha 1B adrenoceptor expressed in rat-1 fibroblasts. | 29 | assay format | Scientific Literature | |||
| 6. | ALA642028 | F | Potency against cloned human alpha 1D-adrenoceptor expressed in rat-1 fibroblasts. | 29 | assay format | Scientific Literature | |||
| 7. | ALA640793 | F | Central hypotensive activity in anesthetized normotensive rats. | 19 | assay format | Scientific Literature | |||
| 8. | ALA640795 | F | Peripheral hypertensive activity in pithed normotensive rats. | 19 | assay format | Scientific Literature | |||
| 9. | ALA646333 | B | Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat brain membranes | Rattus norvegicus | 13 | cell membrane format | Scientific Literature | ||
| 10. | ALA643420 | F | In vitro activation of human alpha-1D receptor expressed in rat-1 fibroblasts via calcium using mobilization through the Gq coupled PLC pathway as functional assay | 31 | assay format | Scientific Literature | |||
| 11. | ALA650231 | F | In vitro activation of human alpha-1A receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as functional assay | 31 | assay format | Scientific Literature | |||
| 12. | ALA649285 | B | Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.2 nM) to rat isolated brain membranes by 50% was reported; 4.1*10e-7 | 1 | tissue-based format | Scientific Literature | |||
| 13. | ALA647555 | B | Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain membranes by 50% was reported; 4.8*10e-9 | 1 | tissue-based format | Scientific Literature | |||
| 14. | ALA875931 | F | In vitro activation of human Alpha-1B receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as functional assay | 31 | assay format | Scientific Literature | |||
| 15. | ALA798414 | F | Hypotensive activity (25% decrease in arterial pressure) after i.v. administration to anesthetized normotensive rats. | Oryctolagus cuniculus | 10 | organism-based format | Scientific Literature | ||
| 16. | ALA798416 | F | Hypertensive activity (increase in arterial pressure to 60 mmHg)) after i.v. administration to pithed rats. | Oryctolagus cuniculus | 23 | organism-based format | Scientific Literature | ||
| 17. | ALA844273 | A | Binding energy by using the equation deltaG obsd = -RT ln KD | 184 | assay format | Scientific Literature | |||
| 18. | ALA1909307 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia | 888 | tissue-based format | Scientific Literature | |||
| 19. | ALA1909308 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis | 888 | tissue-based format | Scientific Literature | |||
| 20. | ALA1909309 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis | 888 | tissue-based format | Scientific Literature |
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