Assay

#	Aladdin ID	Assay Type	Description	Organism	Compounds	BAO Format	Source
1.	ALA928888	B	Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay	Homo sapiens	27	cell-based format	Scientific Literature
2.	ALA928889	F	Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay	Homo sapiens	6	assay format	Scientific Literature
3.	ALA928890	F	Antagonist activity at rabbit CXCR2 by neutrophil chemotaxis assay	Oryctolagus cuniculus	6	assay format	Scientific Literature
4.	ALA3301364	P	ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the method described in J. Assoc. Lab. Autom. 2011, 16, 276-284. Experimental range 0.10 to 1500 uM		1,763	small-molecule physicochemical format	AstraZeneca Deposited Data
5.	ALA3301366	A	ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole rat plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.	Rattus norvegicus	717	cell-free format	AstraZeneca Deposited Data
6.	ALA3301370	A	ASTRAZENECA: Intrinsic clearance measured in human liver microsomes following incubation at 37C. Experimental range <3 to >150 microL/min/mg. Rapid Commun. Mass Spectrom. 2010, 24, 1730-1736.	Homo sapiens	1,102	microsome format	AstraZeneca Deposited Data
7.	ALA3301371	A	ASTRAZENECA: Intrinsic clearance measured in rat hepatocytes following incubation at 37C. Experimental range <3 to >150 microL/min/1E6 cells. Rapid Commun. Mass Spectrom. 2010, 24, 1730-1736	Rattus norvegicus	837	cell-based format	AstraZeneca Deposited Data