# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA859328 | B | Binding of [3H]N-methylscopolamine at porcine heart Muscarinic acetylcholine receptor M2 that inhibits the dissociation of [3H]NMS half maximally (pEC50diss) was reported | Sus scrofa | 9 | ALA1135441 | single protein format | Scientific Literature | |
2. | ALA745569 | B | Ability to dissociate radioligand [3H]NMS from muscarinic acetylcholine receptor M2 of porcine heart | Sus scrofa | 44 | ALA1136755 | single protein format | Scientific Literature | |
3. | ALA745570 | B | Binding of [3H]N-methylscopolamine at porcine heart Muscarinic acetylcholine receptor M2 and negative log of the equilibrium dissociation constant was reported | Sus scrofa | 9 | ALA1135441 | single protein format | Scientific Literature | |
4. | ALA1614257 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) | Homo sapiens | 37,649 | ALA1201862 | assay format | PubChem BioAssays | |
5. | ALA1613777 | A | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | Homo sapiens | 3,557 | ALA1201862 | single protein format | PubChem BioAssays | |
6. | ALA1741321 | F | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
7. | ALA1741322 | F | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
8. | ALA1741323 | F | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
9. | ALA1741324 | F | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
10. | ALA1741325 | F | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
11. | ALA1794499 | F | PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] | 13,676 | ALA1201862 | assay format | PubChem BioAssays | ||
12. | ALA3124688 | B | Antagonist activity at muscarinic M3 receptor in albino guinea pig ileum assessed as inhibition of electrically-induced response | Cavia porcellus | 2 | ALA3120046 | tissue-based format | Scientific Literature | |
13. | ALA3123979 | B | Agonist activity at muscarinic M2 receptor in albino guinea pig left atrium assessed as stimulation of electrically-induced response at 1 uM | Cavia porcellus | 1 | ALA3120046 | single protein format | Scientific Literature | |
14. | ALA3123980 | B | Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay relative to control | Rattus norvegicus | 12 | ALA3120046 | tissue-based format | Scientific Literature | |
15. | ALA3123981 | B | Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay | Rattus norvegicus | 12 | ALA3120046 | tissue-based format | Scientific Literature | |
16. | ALA3123982 | B | Intrinsic activity at muscarinic M3 receptor in albino guinea pig ileum assessed as stimulation of electrically-induced response relative to bethanechol | Cavia porcellus | 12 | ALA3120046 | tissue-based format | Scientific Literature | |
17. | ALA3123983 | B | Intrinsic activity at muscarinic M2 receptor in albino guinea pig left atrium assessed as stimulation of electrically-induced response relative to bethanechol | Cavia porcellus | 12 | ALA3120046 | single protein format | Scientific Literature | |
18. | ALA3123984 | B | Intrinsic activity at muscarinic M1 receptor in New Zealand rabbit vas deferens assessed as stimulation of electrically-induced response relative to McN-A-343 | Oryctolagus cuniculus | 12 | ALA3120046 | tissue-based format | Scientific Literature | |
19. | ALA3124178 | B | Antagonist activity at muscarinic M1 receptor in New Zealand rabbit vas deferens assessed as inhibition of electrically-induced response | Oryctolagus cuniculus | 2 | ALA3120046 | tissue-based format | Scientific Literature |