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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA909848 B Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cells Homo sapiens 16 ALA1138214 cell-based format Scientific Literature 2. ALA912816 B Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cells Homo sapiens 13 ALA1138214 cell-based format Scientific Literature 3. ALA912817 A AUC (0-6h) in rat at 10 mg/kg, po Rattus norvegicus 13 ALA1138214 organism-based format Scientific Literature 4. ALA912819 F Inhibition of CXCL8-induced human neutrophil chemotaxis Homo sapiens 3 ALA1138214 assay format Scientific Literature 5. ALA912820 F Inhibition of CXCL1-induced human neutrophil chemotaxis Homo sapiens 3 ALA1138214 assay format Scientific Literature 6. ALA929862 B Displacement of [125I]IL8 from human CXCR2 by SPA assay Homo sapiens 22 ALA1141536 single protein format Scientific Literature 7. ALA963305 B Binding affinity to CXCR2 22 ALA1153270 single protein format Scientific Literature 8. ALA963306 B Binding affinity to CXCR1 22 ALA1153270 single protein format Scientific Literature 9. ALA963307 A AUC in po dosed rat Rattus norvegicus 7 ALA1153270 organism-based format Scientific Literature 10. ALA1055928 B Displacement of human [125I]IL-8 from human CXCR1 Homo sapiens 26 ALA1153641 single protein format Scientific Literature 11. ALA1055929 B Displacement of human [125I]IL-8 from human CXCR2 Homo sapiens 34 ALA1153641 single protein format Scientific Literature 12. ALA1055930 A AUC in rat at 10 mg/kg, po Rattus norvegicus 12 ALA1153641 organism-based format Scientific Literature 13. ALA3301363 P ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 4,197 ALA3301361 small-molecule physicochemical format AstraZeneca Deposited Data 14. ALA3301364 P ASTRAZENECA: Solubility in pH7.4 buffer using solid starting material using the method described in J. Assoc. Lab. Autom. 2011, 16, 276-284. Experimental range 0.10 to 1500 uM 1,763 ALA3301361 small-molecule physicochemical format AstraZeneca Deposited Data 15. ALA3301370 A ASTRAZENECA: Intrinsic clearance measured in human liver microsomes following incubation at 37C. Experimental range <3 to >150 microL/min/mg. Rapid Commun. Mass Spectrom. 2010, 24, 1730-1736. Homo sapiens 1,102 ALA3301361 microsome format AstraZeneca Deposited Data 16. ALA3301371 A ASTRAZENECA: Intrinsic clearance measured in rat hepatocytes following incubation at 37C. Experimental range <3 to >150 microL/min/1E6 cells. Rapid Commun. Mass Spectrom. 2010, 24, 1730-1736 Rattus norvegicus 837 ALA3301361 cell-based format AstraZeneca Deposited Data 17. ALA5215021 B Inhibition of human CXCR1 Homo sapiens 3 ALA5214881 single protein format Scientific Literature