# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA926128 | F | Analgesic activity in SNL nerve injury in iv dosed rat model | Rattus norvegicus | 4 | ALA1141459 | organism-based format | Scientific Literature | |
2. | ALA2443741 | T | Toxicity in Sprague-Dawley rat assessed as spontaneous locomotor activity at 10 mg/kg, iv after 10 mins by rotorod test | Rattus norvegicus | 1 | ALA2439980 | organism-based format | Scientific Literature | |
3. | ALA2443743 | F | Analgesic activity in rat assessed reduction formalin-induced second phase pain response at 10 mg/kg, iv administered 8 mins post formalin challenge | Rattus norvegicus | 1 | ALA2439980 | organism-based format | Scientific Literature | |
4. | ALA2443745 | F | Analgesic activity in rat assessed reduction formalin-induced initial pain response at 10 mg/kg, iv administered 2 mins before formalin challenge | Rattus norvegicus | 1 | ALA2439980 | organism-based format | Scientific Literature | |
5. | ALA2443746 | F | Analgesic activity in STZ-induced diabetic neuropathy rat model assessed as prolongation of reversal of hypersensitivity time at 3 mg/kg, iv measured after 15 to 90 mins relative to vehicle-treated control | Rattus norvegicus | 1 | ALA2439980 | organism-based format | Scientific Literature | |
6. | ALA2443747 | A | Drug uptake in Sprague-Dawley rat brain at 1 mg/kg, iv measured after 1 hr | Rattus norvegicus | 2 | ALA2439980 | organism-based format | Scientific Literature | |
7. | ALA2443748 | A | Drug uptake in Sprague-Dawley rat brain at 1 mg/kg, iv measured after 15 mins | Rattus norvegicus | 2 | ALA2439980 | organism-based format | Scientific Literature | |
8. | ALA2444332 | F | Analgesic activity in Sprague-Dawley rat L5/L6 spinal nerve injury Chung model of neuropathic pain assessed as reduction of von Frey hair-induced paw withdrawal threshold at 3 mg/kg, iv measured after 15 to 90 mins relative to vehicle-treated control | Rattus norvegicus | 1 | ALA2439980 | organism-based format | Scientific Literature | |
9. | ALA2444334 | F | Analgesic activity in Sprague-Dawley rat L5/L6 spinal nerve injury Chung model of neuropathic pain assessed as reduction of von Frey hair-induced paw withdrawal threshold at 10 mg/kg, iv measured after 15 mins relative to vehicle-treated control | Rattus norvegicus | 2 | ALA2439980 | organism-based format | Scientific Literature | |
10. | ALA2444335 | B | Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay relative to retigabine | Mus musculus | 1 | ALA2439980 | cell-based format | Scientific Literature | |
11. | ALA2444336 | B | Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay relative to (+/-)-N-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)-3-(2-chlorophenyl)acrylamide | Mus musculus | 7 | ALA2439980 | cell-based format | Scientific Literature | |
12. | ALA2444337 | B | Induction of mouse KCNQ2 expressed in HEK293 cells at -40 mV holding potential by whole-cell patch clamp assay | Mus musculus | 9 | ALA2439980 | cell-based format | Scientific Literature |